Carl Feng

Professor Carl Feng is a Professor in the Discipline of Infectious Diseases and Immunology in the School of Medical Sciences, Faculty of Medicine and Health at the University of Sydney. He holds MD and PhD degrees. Professor Feng completed his PhD at the Centenary Institute in the Mycobacterial Research group from February 1997 to November 2000. From June 2005 to July 2012, he worked as a Researcher in the Laboratory of Parasitic Diseases at the National Institute of Allergy and Infectious Diseases, National Institutes of Health. He joined the University of Sydney as Associate Professor in the same discipline from August 2012 to December 2015 before being promoted to full Professor.

An immunologist, Professor Feng investigates how the immune system detects, responds to, and controls respiratory pathogens, defining fundamental cellular and molecular mechanisms that regulate host immunity to major respiratory pathogens such as Mycobacterium tuberculosis. His research interests include immunology of infectious diseases, innate immunity, inflammation, tuberculosis, immunity, cell culture, flow cytometry, and autoimmunity. He has produced 144 publications cited over 14,655 times. Key publications include 'Tissue-wide profiling of human lungs reveals spatial sequestration of macrophages in tuberculosis' (2025), 'A CD40-OX40 co-stimulatory circuit orchestrates protective CD4+ T cell immunity in tuberculosis' (2026), 'Mycobacterium tuberculosis-derived linoleic acid increases regulatory T cell function to promote bacterial survival within macrophages' (2025), 'Spatial mapping reveals granuloma diversity and histopathological superstructure in human tuberculosis' (2023), 'Bacterial-induced or passively administered interferon gamma conditions the lung for early control of SARS-CoV-2' (2023), 'Stromal structure remodeling by B lymphocytes limits T cell activation and promotes chronic tuberculosis' (2022), and 'The quality of energy- and macronutrient-balanced diets regulates host susceptibility to Mycobacterium tuberculosis infection' (2022). Professor Feng leads research in infection, immunity, and inflammation.

Professional Email: carl.feng@sydney.edu.au