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5.05/4/2026

A true inspiration to all who learn.

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About Christopher

Professor Christopher Loughrey is Professor of Experimental Cardiology in the School of Cardiovascular and Metabolic Health at the University of Glasgow. A qualified veterinary surgeon, he earned his BVMS in 2000 and PhD in 2003 from the University of Glasgow. In 2005, he established his independent research group within the Glasgow Cardiovascular Research Centre, pioneering novel animal models to investigate human cardiac diseases such as myocardial infarction and heart failure. His research adopts an integrative approach to explore the pathophysiology of heart disease, with a focus on excitation-contraction coupling in cardiomyocytes, sarcoplasmic reticulum-mediated calcium handling, adverse cardiac remodelling, ischaemia-reperfusion injury, myocarditis, and cathepsin activity. Current efforts target therapeutic interventions for heart failure with preserved ejection fraction (HFpEF), including inhibition of ryanodine receptors and runt-related transcription factors like RUNX1. Methodologies employed include confocal microscopy, single-cell electrophysiology, fluorescence imaging, Western blotting, RT-qPCR, isolated heart perfusions, and in vivo phenotyping via echocardiography and pressure-volume analysis.

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