Rate My Professor David Schneider

Schneider's research centers on the mechanisms by which cells control gene expression at the transcription level, with emphasis on ribosome biosynthesis and regulation of gene expression. His laboratory investigates early steps in ribosome biosynthesis, enzymatic properties of RNA polymerases I, II, and III, transcription elongation kinetics, and strategies to inhibit ribosome synthesis for therapeutic applications such as antifungals and cancer treatments. Key publications include "RNA Polymerase I Is Uniquely Vulnerable to the Small Molecule BMH-21" (2022), "The small-molecule BMH-21 directly inhibits transcription elongation by RNA Polymerase I" (2022), "Uncovering the mechanisms of transcription elongation by RNA polymerase I" (2022), "Growth-phase-dependent control of rRNA synthesis in Saccharomyces cerevisiae" (2024), and "Global kinetic mechanism describing single nucleotide incorporation for RNA polymerase I reveals fast UMP incorporation" (2024). Schneider received the UAB Graduate Dean's Award for Excellence in Mentorship in 2014 and 2023. He teaches multiple courses and mentors graduate students and junior faculty, with research supported by National Institutes of Health grants.