
Always positive, enthusiastic, and supportive.
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Erica Mandell, DO, serves as an Associate Professor in Pediatrics-Neonatology at the University of Colorado School of Medicine on the Anschutz Medical Campus. She received her Doctor of Osteopathic Medicine from the Kansas City University of Medicine and Biosciences College of Osteopathic Medicine in 2008. Board certified in Pediatrics, she practices Neonatal-Perinatal Medicine at Children's Hospital Colorado Anschutz Medical Campus, where she addresses neonatal respiratory conditions including persistent pulmonary hypertension of the newborn and hypoxemic respiratory failure.
Dr. Mandell's research centers on bronchopulmonary dysplasia (BPD) and associated pulmonary hypertension, antenatal inflammation, vitamin D deficiency and therapeutic interventions, lung development, pulmonary vascular phenotypes, and ventilator-induced lung injury. Her investigations examine the impacts of antenatal endotoxin, intraamniotic exposures such as sFlt-1, and maternal vitamin D deficiency on lung structure, function, and vascular growth in experimental models. She explores pulmonary vasodilator strategies, disease phenotyping in severe BPD including dysanapsis, cholestasis, and thrombocytopenia, and perinatal hypoxia-inducible factor stabilization to preserve alveolar and vascular growth. Key publications include 'Development of late pulmonary hypertension after antenatal inflammation in experimental bronchopulmonary dysplasia' (Pediatr Res, 2025), 'Intraamniotic vitamin D preserves lung development and prevents pulmonary hypertension in experimental bronchopulmonary dysplasia due to intraamniotic sFlt-1' (Am J Physiol Lung Cell Mol Physiol, 2025), 'Bronchopulmonary Dysplasia–Associated Pulmonary Hypertension: Basing Care on Physiology' (Neoreviews, 2024), 'Dysanapsis as a Determinant of Lung Function in Development and Disease' (Am J Respir Crit Care Med, 2023), 'Persistent pulmonary hypertension of the newborn' (Pediatr Pulmonol, 2021), and 'Vitamin D Deficiency in Development: How Much Is Enough, and How Much Is Too Much?' (Am J Respir Cell Mol Biol, 2021). She has presented on topics such as 'Vitamin D Role in Lung Disease and Development' in the Pediatrics Basic & Translational Research Seminar Series and contributes to the Neonatology Basic Science fellowship program, focusing on lung growth, pulmonary vascular function, and clinical trials involving inhaled nitric oxide.

Photo by Osarugue Igbinoba on Unsplash
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