Rate My Professor Galina Mukamolova

Mukamolova's research centers on bacterial dormancy and resuscitation, focusing on Mycobacterium tuberculosis, the causative agent of tuberculosis, and Burkholderia pseudomallei, the agent of melioidosis. She discovered resuscitation-promoting factors (Rpf), which revealed occult populations of tubercle bacilli and has had lasting impact on tuberculosis research. Her investigations cover the clinical importance of Rpf-dependent mycobacteria, in vitro models for drugs targeting persister mycobacteria, molecular protein kinase signalling mechanisms, and peptidoglycan recycling. This work is funded by BBSRC, MRC, Royal Society, European Commission, and industry. Notable publications include 'A bacterial cytokine' (Proc. Natl. Acad. Sci. USA, 1998), 'The rpf gene of Micrococcus luteus encodes an essential secreted growth factor' (Mol. Microbiol., 2002), 'A family of autocrine growth factors in Mycobacterium tuberculosis' (Mol. Microbiol., 2002), 'Resuscitation-promoting factors reveal an occult population of tubercle bacilli in sputum' (Am. J. Respir. Crit. Care Med., 2010), 'Phenotypically adapted Mycobacterium tuberculosis populations from sputum are tolerant to first line drugs' (Antimicrob. Agents Chemother., 2016), 'Two faces of CwlM, an essential PknB substrate, in Mycobacterium tuberculosis' (Cell Rep., 2018), 'Mycobacterial phosphatase PstP regulates global serine threonine phosphorylation and cell division' (Sci. Rep., 2019), and 'Coupling of Peptidoglycan Synthesis to Central Metabolism in Mycobacteria: Post-transcriptional Control of CwlM by Aconitase' (Cell Rep., 2020).