Graham Mann

Professor Graham Mann is a Professor in the Westmead Clinical School, Faculty of Medicine and Health, at the University of Sydney, where he holds honorary appointments including Conjoint Professor of Genomic Medicine and principal investigator at Melanoma Institute Australia. He earned his MBBS and PhD from the University of Sydney, trained in medical oncology, and holds FRACP qualifications, with postdoctoral research on cell proliferation at the Ludwig Institute for Cancer Research and the University of Umeå, Sweden. His career trajectory includes establishing a full-time cancer genetics research program at the Westmead campus of Sydney Medical School in partnership with Rick Kefford, heading the Melanoma Translational Research Group at Westmead Institute for Medical Research, and directing the John Curtin School of Medical Research at the Australian National University from 2019 to 2024. Mann has secured sustained NHMRC Program Grants for 16 years, a Centre of Research Excellence in Melanoma, and project grants totaling millions, reflecting his leadership in multidisciplinary translational research.

Mann's research focuses on all aspects of melanoma control, including the genetics of melanoma risk in families and the population, environmental and psychological factors, sunbed use in young adults, and molecular markers and targets for improved diagnosis and treatment. He co-leads highly translational programs supported by NHMRC grants, initiated the Australian Melanoma Genome Project as co-PI, contributed to the GenoMEL consortium and Australian kConFab breast cancer genetics consortium, and serves on the Scientific Steering Committee of the International Cancer Genome Consortium. With 210 primary research papers cited over 64,000 times and an h-index of 47, key publications include 'Genomic Classification of Cutaneous Melanoma' (Cell, 2015), 'Genome-wide association study identifies three new melanoma susceptibility loci' (Nature Genetics, 2011), and 'DNA Methylation Classes of Stage II and III Primary Melanomas and Their Clinical and Prognostic Significance' (2024). His contributions extend to the MelCOR Australian Clinical Outcomes Register, ACRF Centre for Excellence in Melanoma Diagnosis, and interim directorship of the National Centre for Indigenous Genomics. Awards include the Professor J.A. Young Medal (2010) for excellence in research and service to the University of Sydney, NSW Premier’s Awards for Excellence in Translational Cancer Research (2009, 2017), NSW Premier’s Wildfire Award (2014), RACP Roche Fellowship (1987), and University of Sydney Medical Foundation Scholarship (1987-1988).

Professional Email: graham.mann@sydney.edu.au