Rate My Professor Graham Murray

Murray's research examines the causes, brain mechanisms, and treatments of mental disorders, primarily psychosis and depression. He utilizes epidemiology, neuroscience, computational psychiatry, genomics, electronic health records, and clinical trials to explore relationships between cognitive development across the lifespan and mental illness, as well as how etiological factors such as genetics lead to pathophysiological disruptions. His interests include applications of polygenic risk scores and clinical informatics risk prediction models. He jointly leads the early psychosis workstream of the NIHR Mental Health Translational Research Collaboration and the Office of Life Sciences/NIHR Mental Health Mission, and is chief investigator of the Early Psychosis Mission to enhance UK psychosis translational research infrastructure. Key publications include 'Predicting treatment resistance from first-episode psychosis using routinely collected clinical information' (2023, Nature Mental Health), 'Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes' (2023, Nature Genetics), 'Educational attainment, structural brain reserve and Alzheimer’s disease: a Mendelian randomization analysis' (2023, Brain), and 'Impaired reinforcement learning following chronic escitalopram as revealed by computational modelling and neuroimaging correlates' (2024, Neuroscience Applied).