Rate My Professor Hal Broxmeyer

Broxmeyer's research focused on the regulation of hematopoiesis and hematopoietic stem and progenitor cells, pioneering umbilical cord blood as a transplantable source. His seminal 1989 paper, 'Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells,' demonstrated its viability, enabling the first successful cord blood transplant in 1988 for a patient with Fanconi anemia. Innovations included expanding cord blood cells under hypoxic conditions to triple yields and elucidating roles of chemokines and cytokines in stem cell homing, engraftment, mobilization, and survival. He authored 838 peer-reviewed publications, cited over 73,000 times with an h-index of 127, including key works like 'Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist' (2005) and 'Umbilical cord blood transplantation: the first 25 years and beyond' (2013). Broxmeyer received major awards such as the E. Donnall Thomas Prize (2007), presidency of the American Society of Hematology (2010, first PhD president), Donald Metcalf Award (2011), IU President's Medal (2019), and Lifetime Achievement Award from the Cord Blood Association (2019). His contributions enabled over 40,000 cord blood transplants worldwide, transforming treatments for leukemia, lymphoma, sickle cell disease, and other disorders. He mentored numerous investigators, served on NIH study sections, editorial boards, and led societies including the International Society for Experimental Hematology.