Rate My Professor Isis Trujillo-Gonzalez

Isis Trujillo-Gonzalez is a Research Assistant Professor in the Department of Nutrition at the University of North Carolina at Chapel Hill's Nutrition Research Institute, a position she has held since 2021. Prior to this, she completed postdoctoral training in Nutritional Neuroscience at the same institute from 2015 to 2020. She holds a B.S. in Biology, graduated with honors from the National Autonomous University of Mexico in 2009, and a Ph.D. in Biomedical Sciences, also with honors from UNAM in 2014. Her early career included roles as a graduate research associate in Genomic Medicine and Environmental Toxicology at UNAM and undergraduate research assistant in Pharmacology.

Trujillo-Gonzalez's research centers on nutritional neuroscience, particularly how choline and one-carbon metabolism program neural progenitor fate, epigenetic circuits in the brain, and trajectories of neurodevelopmental diseases and neurodegeneration. She develops choline-informed precision nutrition strategies using mouse models, human cohorts, and cell-based mechanistic studies. Key publications encompass "Choline and Betaine concentrations in plasma predict dietary choline intake in healthy humans: a double-blind randomized controlled feeding study" (The American Journal of Clinical Nutrition, 2025), "Integrating in silico approaches in nutrition and brain health" (The Journal of Nutrition, 2025), "Urinary signatures are associated with calorie restriction-mediated weight loss in obese diversity outbred mice" (PLOS One, 2025), "The role of prenatal choline and its impact on neurodevelopmental disorders" (Frontiers in Nutrition, 2024), "Choline Regulates SOX4 through miR-129-5p and Modifies H3K27me3 in the Developing Cortex" (Nutrients, 2023), and "Low availability of choline in utero disrupts development and function of the retina" (The FASEB Journal, 2019). She has earned recognition including the Nutrition Research Institute Impact Award for Cultural Stewardship (2023), first place in the postdoctoral poster competition at the 12th International Conference on One Carbon Metabolism (2019), and a CONACyT Pre-Doctoral Research Fellowship (2009-2014). Additionally, she co-directs the Animal Metabolism Phenotyping Core of the NORC since 2025, serves as guest associate editor for Frontiers in Pharmacology and Nutrients, participates in committees such as the UNC Wellness Committee, and presents invited lectures on choline biomarkers and nutrigenomics at international conferences.