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Rate My Professor Jane McKeating

University of Oxford

Ratings & reviews

5.05/4/2026

Brings enthusiasm and expertise to class.

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About Jane

Professor Jane McKeating is Professor of Molecular Virology in the Nuffield Department of Medicine within the Medical Sciences Division at the University of Oxford. She leads the McKeating Group, which investigates viruses as intracellular pathogens and the host pathways that define susceptibility to viral infection and associated disease progression. Employing advanced techniques such as spatial mapping of infected cells at single-cell resolution, her team identifies factors regulating virus tissue tropism. Current research centers on hepatitis B and D viruses, major causes of chronic liver disease and hepatocellular carcinoma. Studies explore the roles of hypoxia-inducible factors in viral transcription, hepatocyte-intrinsic and extrinsic pathways influencing host susceptibility, and spatial transcriptional profiling alongside single-molecule resolution imaging to elucidate virus-host interactions. Additional work examines respiratory viruses, including demonstrations that hypoxia suppresses SARS-CoV-2 replication and inflammatory responses, while hypoxia-inducible factor mimetic drugs inhibit infection by activating innate immune sensing and interferon signaling pathways.

Rate My Professor Jane McKeating | University of Oxford