Rate My Professor Nagy Habib

Professor Nagy Habib, MB BCh, ChM, FRCS (Ed), is Professor of Hepatobiliary Surgery in the Department of Surgery and Cancer, Faculty of Medicine, at Imperial College London, a position he has held since July 2003. He serves as Head of the Section of Hepatopancreatobiliary Surgery and Director of the Hepatopancreatobiliary (HPB) Unit at Hammersmith Hospital. As an active surgeon specializing in procedures for liver cancer, pancreatic cancer, biliary disorders, and cholecystectomy, he has overseen outcomes where north west London achieves the best one-year, three-year, five-year, and ten-year survival figures in England for liver cancer patients—about three times the national average—and superior survival rates for pancreatic cancer patients. The unit reports the lowest 30-day operative mortality in Europe at 1.3% across 1,000 consecutive liver resections.

A pioneering translational researcher, Professor Habib led the first clinical trial of plasmid and adenovirus for liver cancer treatment and advanced hydrodynamic gene delivery with plasmid therapy. He served as principal investigator for world-first trials using adult bone marrow-derived stem cells for liver insufficiency and CD34+ cells for stroke patients. His inventions include the Habib™ 4X radiofrequency device for bloodless liver resection, licensed to AngioDynamics and applied in over 70,000 patients worldwide, and the Habib™ EndoHPB catheter for palliation of pancreatic and biliary cancers, acquired by Boston Scientific and recipient of the Gold Edison Award for Medical Innovation in 2020; these stemmed from the Imperial spin-out EMcision Limited. Currently, he organizes Phase I/II trials for MTL-CEBPA small activating RNA (saRNA) therapy in liver cancer and cirrhosis (OUTREACH, TIMEPOINT, OUTREACH2 studies) and develops RNA aptamers for targeted siRNA delivery in pancreatic cancer. With more than 340 peer-reviewed publications, his contributions have profoundly influenced hepatobiliary surgery, oncology, and interventional therapies. Honors include election to the French Academy of Surgeons, the European Surgical Association, and selection as one of the top 10 surgeons in the UK by The Saturday Times Magazine.