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Professor Dame Pamela J Shaw is an academic neurologist and Professor of Neurology at the University of Sheffield, where she has held her position since 2000. She graduated in Medicine with first-class honours from the University of Newcastle in 1979, completed her MRCP and specialist training in neurology there, and was awarded an MD with commendation in 1988 for research on neurological complications of coronary bypass surgery. She held a Wellcome Senior Fellowship in Clinical Science from 1991 to 2001 and was appointed Professor of Neurological Medicine at the University of Newcastle in 1997 before moving to Sheffield.
At Sheffield, Professor Shaw serves as Director of the Sheffield Institute for Translational Neuroscience (SITraN) since 2010, Director of the NIHR Biomedical Research Centre for Translational Neuroscience for Chronic Neurological Disorders, Director of the Sheffield Care and Research Centre for Motor Neuron Disorders, and Director of the Cross-Faculty Neuroscience Institute since 2019. She is also an Honorary Consultant Neurologist at Sheffield Teaching Hospitals NHS Foundation Trust. Her research focuses on motor neuron disease (MND), including genetic subclassification, identification of disease pathways, development of neuroprotective therapies such as riluzole and gene therapies, and evaluation of non-invasive ventilation. She has authored over 560 publications with an H-index of 116, secured more than £140 million in research funding, and supervised over 190 researchers including 55 PhD students. Her contributions have been recognised with numerous awards including the DBE for services to neuroscience in 2014, the NIHR Senior Investigator Award, the American Academy of Neurology Sheila Essey Award, and the Queen’s Anniversary Award to SITraN in 2019. She previously served as Pro-Vice Chancellor for the Faculty of Health from 2016 to 2019 and has held leadership roles in national and international neurological research organisations.
Explore the latest Motor Neurone Disease treatment advancements, including a new drug in a late-stage UK trial promising to slow ALS progression. UK universities like Sheffield and Oxford lead the way.
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