GTPase MASLD Fibrosis Breakthrough | NUS Research Singapore
Discover the latest GTPase signaling breakthrough in MASLD fibrosis from Lund University and NUS, implications for Singapore's 40% prevalence, and local innovations.
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Philipp Kaldis is a professor in metabolic disorders and liver disease at the Department of Clinical Sciences at Lund University. He serves as vice-coordinator of the Lund University Diabetes Centre (LUDC) and contributes to the leadership of the centre. He also holds the position of Special Chief Editor for the Cell Growth and Division section at the journal Frontiers in Cell and Developmental Biology. Kaldis received his PhD from ETH Zürich in Switzerland. He completed a postdoc at Yale University School of Medicine in the United States and established his own laboratory at the National Cancer Institute at the National Institutes of Health in the United States, where he was later promoted to Senior Investigator. He subsequently moved to Singapore to work at the Institute of Molecular Cell Biology at A*STAR and the National University of Singapore before joining Lund University in 2019.
Kaldis was trained as a biochemist and uses genetically modified organisms in his laboratory to investigate cell cycle regulation and human disease. Over the past decade, his research has focused on the liver, including liver regeneration, liver cancer, and metabolism. His current work examines metabolic changes in the context of fatty liver disease and diabetes, employing approaches from cell biology, genetics, metabolomics, lipidomics, and genomics to identify deregulated pathways and mechanisms. This research aims to advance understanding of liver disease and diabetes and to support the development of new therapeutic strategies. Kaldis is a member of the Lund University Cancer Centre and the strategic research area EXODIAB: Excellence of Diabetes Research in Sweden.
Discover the latest GTPase signaling breakthrough in MASLD fibrosis from Lund University and NUS, implications for Singapore's 40% prevalence, and local innovations.