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Raghu G. Mirmira, MD, PhD, is a physician-scientist specializing in diabetes, β-cell biology, and translational endocrinology. He is a tenured Professor of Medicine at the University of Chicago, where he serves as Director of the NIH-funded Diabetes Research and Training Center, Vice Chair for Research in the Department of Medicine, and Director of the Medical Scientist Training Program. He completed his BA with honors in chemistry, MD with honors, and PhD at the University of Chicago. He then pursued residency and fellowship training at the University of California, San Francisco, where he was a Howard Hughes Physician Postdoctoral Fellow. Dr. Mirmira joined the University of Chicago faculty in 2019 after previous positions including as MSTP Director at Indiana University.
Dr. Mirmira’s research focuses on the mechanisms leading to pancreatic β-cell dysfunction and loss in diabetes, including transcriptional control of β-cell identity, inflammatory pathways such as 12-lipoxygenase, and stress-response mechanisms. His laboratory has contributed to biomarkers reflecting β-cell stress and injury in type 1 diabetes and maintains continuous NIH funding for more than two decades as PI or MPI on multiple R01, U01, and P30 grants. He is an elected member of the American Society for Clinical Investigation and the Association of American Physicians and received the Albert Renold Award from the American Diabetes Association for contributions to mentorship and training. He remains active in clinical endocrinology at UChicago Medicine.
University of Chicago researchers unveil mRNA-loaded nanoparticles that deliver protective genes to pancreatic beta cells, delaying type 1 diabetes in mice and showing human potential. Explore the Cell Reports Medicine study.
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