
University of California Irvine
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Shlomit Radom-Aizik is Professor in the Department of Pediatrics at the University of California, Irvine School of Medicine. She serves as Exercise Medicine Division Chief in Pediatrics and Executive Director of the Research Center for Exercise Medicine and Sleep (RCEMS), previously the Pediatric Exercise and Genomics Research Center (PERC). She earned her Ph.D. in Physiology and Pharmacology from Tel Aviv University, Sackler Faculty of Medicine, Israel. As a molecular biologist and exercise physiologist, her research centers on functional genomics and exercise physiology to reveal the molecular mechanisms by which exercise influences health and disease, with a particular emphasis on pediatric populations. Her work investigates exercise effects on gene expression, immune cells, cardiopulmonary responses, and conditions such as sickle cell anemia and sleep-related fitness.
Radom-Aizik is Principal Investigator (mpI) on NIH grants including U01AR071158 (2016-2025) for the Pediatric Clinical Center in the Molecular Transducers of Physical Activity Consortium (MoTrPAC) and U01TR002004 (2018-2024) for advancing exercise testing and physical activity assessment in children. She is Co-Investigator on NIH R01HL153807 (2021-2025) examining mechanisms of sleep and aerobic fitness in children and NIH R01 (2017-2024) on pro-inflammatory effects of acute exercise in children with sickle cell anemia. Key publications include "Dynamics of gas exchange and heart rate signal entropy in standard cardiopulmonary exercise testing during critical periods of growth and development" (Physiol Rep, 2024), "Signal Variability Comparative Analysis of Healthy Early- and Late-Pubertal Children during Cardiopulmonary Exercise Testing" (Med Sci Sports Exerc, 2024), "Impact of brief exercise on circulating monocyte gene and microRNA expression: implications for atherosclerotic vascular disease" (Brain Behav Immun, 2014), "Growth inhibition and compensation in response to neonatal hypoxia in rats" (Pediatr Res, 2013), and "Impact of brief exercise on peripheral blood NK cell gene and microRNA expression in young adults" (J Appl Physiol, 2013). She received the 2021 UCI School of Medicine Outstanding Mid-Career Faculty Clinical Research Award and is a member of the American College of Sports Medicine (ACSM), North American Society of Pediatric Exercise Medicine (NASPEM), European College of Sport Science (ECSS), and International Society of Exercise Immunology (ISEI).
Professional Email: saizik@uci.edu