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Professor Toshiharu Ninomiya serves as Professor in the Faculty of Medical Sciences, Department of Basic Medicine at Kyushu University, with concurrent appointments in the Center for Cohort Studies, Graduate School of Medical Sciences Department of Medicine, Graduate School of Medical Sciences Department of Health Care Administration and Management, and School of Medicine Department of Medicine. He earned his Ph.D. (Dr. of Medical Science) from the Faculty of Medicine at Kyushu University in 2000, following completion of his medical studies at the same institution in 1993. His academic career at Kyushu University includes his appointment as Professor in the Faculty of Medical Sciences beginning in June 2016 and a concurrent professorial role from May 2014.
Professor Ninomiya leads the Hisayama Study, a long-running community-based cohort investigation focused on the epidemiology of dementia, stroke, ischemic heart disease, chronic kidney disease, hypertension, and related conditions in a Japanese population. His research interests encompass diabetes, cohort studies, stroke, dementia, nephrology, total mortality, epidemiology, and cardiovascular disease. He has received several awards, including the Imura Clinical Research Encouragement Award in 2010 for work on the relationship between chronic kidney disease and cardiovascular disease, the Young Investigator Award from the International Society of Nephrology in 2010, and ISH Visiting Postdoctoral Awards in 2007 and 2008 for studies on blood pressure and chronic kidney disease. Key publications include “Thirty-seven-year trends in the prevalence, incidence, and prognosis of dementia in a Japanese community: the Hisayama study” (2025), “Serum ergothioneine and risk of dementia in a general older Japanese population: the Hisayama Study” (2025), and multiple papers on cardiovascular and renal outcomes derived from the Hisayama cohort. Professor Ninomiya contributes to public health activities supporting Fukuoka Prefecture, Fukuoka City, and Hisayama Town through data analysis from the study and participates in international collaborative research on dementia, cardiovascular disease, and chronic kidney disease.
A major Kyushu University study examines how the APOE ε4 gene interacts with modifiable risk factors in dementia among older Japanese adults, offering key insights for higher education and public health.
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