Associate Professor Xin-Ming Chen serves in the Northern Clinical School, Faculty of Medicine and Health at the University of Sydney, with his primary affiliation at the Kolling Institute of Medical Research, Royal North Shore Hospital. His research specializes in the molecular and cellular mechanisms of chronic kidney disease, particularly diabetic kidney disease and renal fibrosis. Chen investigates critical pathways such as autophagy dysfunction, mitochondrial quality control, and ion channel activities in renal pathology.

Having joined the University of Sydney in 2003 and holding a PhD in Biochemistry, Chen has published extensively on these topics. Key works include "KCa3.1 Mediates Dysregulation of Mitochondrial Quality Control in Diabetic Kidneys" (2021), "KCa3.1 mediates dysfunction of tubular autophagy in diabetic kidneys" (2016), "Blockade of KCa3.1 Ameliorates Renal Fibrosis Through the TGF-β1/Smad Signaling Pathway in Diabetic Kidney" (2013), "Thioredoxin-interacting protein mediates dysfunction of autophagy and apoptosis in podocytes under hyperglycemia" (2014), and "A single-domain i-body, AD-114, attenuates renal fibrosis through CXCR4 antagonism" (2022). His Google Scholar profile shows over 17,000 citations and an h-index of 39. Chen has obtained major funding, including an NHMRC Ideas Grant of $880,000, Kidney Health Australia funding for stem cell-derived exosomes in CKD prevention, and University of Sydney Ignition Seed Funds. His studies explore therapeutic interventions like photobiomodulation and mesenchymal stem cell-derived extracellular vesicles for kidney injury.

Professional Email: xin-ming.chen@sydney.edu.au