Assistant Researcher

Position Overview

A research assistant position is available in the Macdonald lab in the Department of Molecular Biosciences at the University of Kansas. We explore the genetic basis of complex trait variation using the fruit fly Drosophila as a model system, working on a diverse set of traits, including response to heavy metals and other toxicants, and lifespan/aging.

The successful candidate will help maintain fly strains and populations of flies, supervise and carry out large-scale phenotyping screens, and perform a range of molecular biology procedures, including generating next-generation sequencing libraries for various genomics applications.

We are looking for an enthusiastic and organized individual who wants to learn new skills and has excellent oral and written communication skills. Previous research assistants in the Macdonald group have undertaken independent research projects and have been authors on research publications from the lab. The position is funded through NIH grants and has an anticipated start date of June 1, 2026 (although this is very flexible/negotiable).

Job Description

50% - Generate, maintain and use Drosophila strains/populations for genetic analysis. Examples of the work include stock maintenance, preparing media, carrying out crosses, and assaying strains/populations for phenotypic variation (e.g., stress tolerance).

30% - Carry out a range of molecular biology procedures. Examples of the work include DNA and RNA isolation, PCR, and next-generation sequencing library construction (e.g., for RNAseq or whole-genome sequencing).

10% - Perform general lab tasks, including inventory and ordering of supplies, and working with undergraduate students.

10% - Keep accurate and detailed records. Maintain an up-to-date and accurate lab notebook, keep a detailed digital record of all experimental results, and regularly present data/results to Dr. Macdonald.

Required Qualifications

1. High school diploma/GED and four years of related experience OR Bachelor's degree in a related field.
2. Previous experience with molecular biology techniques (e.g., PCR), as evidenced by the application materials.
3. Effective written communication skills as evidenced by the application materials.

Preferred Qualifications

1. Bachelor's degree in biology or related field.
2. Experience with Drosophila husbandry.
3. Significant laboratory experience, including troubleshooting and optimizing protocols.
4. Experience making next generation sequencing libraries (e.g., RNAseq libraries).
5. Prior experience managing large scientific projects, including managing undergraduate assistants.

Contact Information to Applicants

Stuart Macdonald
sjmac@ku.edu
(785) 864-5362

Additional Candidate Instruction

A complete electronic application includes the following materials:

• CV/resume
• cover letter outlining relevant experience and interest in the position
• contact information for three references (phone/email)

Informal queries about the position are welcome, and can be directed to Stuart Macdonald (sjmac@ku.edu).

Review of applications will begin on Tuesday, April 14, 2026 and will continue until the position is filled.