Clinical and Translational Research in Multiple Myeloma: Novel Immunotherapies, Prognostic Biomarkers and Precision Medicine

Is the Job related to staff position within a Research Infrastructure?: No

Offer Description

Art. 1 – Purpose

A selection is announced for the awarding of no. 1 Research Assignment titled: “Clinical and Translational Research in Multiple Myeloma: Novel Immunotherapies, Prognostic Biomarkers and Precision Medicine”, aimed at introducing young scholars to research and innovation, within the research project entitled “Testamentary bequest from Loris Facchin to DIMED for research into multiple myeloma and chronic lymphoproliferative disorders” to be carried out at the Department of Medicine – DIMED, mainly at the Pietro d'Abano Biomedical Campus, via Orus 2/B Padua, and the Venetian Institute of Molecular Medicine (VIMM), via Orus 2 and/or remotely, under the supervision of Prof. Renato Zambello, acting as Tutor.

The Research Assignment, with a duration of 12 months and an annual gross amount, for the recipient, of Euro 28.373,85 is announced in accordance with the current Regulations for the awarding of Research Assignments pursuant to Art. 22-ter of Law 240/2010 within the aforementioned research project, Scientific Disciplinary Group [GSD] 06/MEDS-09 - BLOOD DISEASES, ONCOLOGY AND RHEUMATOLOGY, Scientific Disciplinary Sector [SSD] MEDS-09/B - BLOOD DISEASES.

The Research Assignment, funded by “Testamentary bequest from Loris Facchin to DIMED for research into multiple myeloma and chronic lymphoproliferative disorders”, has as its object the carrying out of the research activity specified below:

• Participation in the design of prospective and retrospective clinical studies in multiple myeloma.
• Clinical data collection and research database management.
• Data evaluation of efficacy and safety of novel immunotherapeutic strategies, with particular focus on bispecific antibodies and other innovative immunotherapies.
• Correlation between clinical features, treatment response, circulating plasma cells characterization, measurable residual disease (MRD) and clinical outcomes.
• Collaboration with the translational research laboratory for integration of biological and clinical data.
• Statistical analysis and dissemination of results through scientific publications and presentations at national and international meetings.

Art. 2 – Admission requirements

Young scholars who hold of a single-cycle master's degree in Medicine and Surgery (LM-41), obtained no more than six years ago, Specialisation in Hematology and have a curriculum suitable for assisting in the performance of research activities are eligible to participate in the selection process.

The following skills and experience, deemed necessary, are also required:

• knowledge of multiple myeloma.
• experience in observational clinical research;
• knowledge of novel therapeutic strategies, including immunotherapies, bispecific antibodies and cellular therapies;
• expertise in prognostic and predictive biomarkers, including measurable residual disease;
• familiarity with flow cytometry and translational laboratory techniques;
• experience in clinical database management and statistical analysis;
• ability to prepare research protocols, scientific manuscripts and conference presentations;
• ability to work within multidisciplinary and collaborative research networks.

The qualifications must be held on the announcement deadline date.

If the degree diploma was obtained abroad, it must be declared equivalent, for selection purposes only, to the master's degree or single-cycle master's degree by the Selection Committee.

Research Assignments, pursuant to Art. 22-ter of Law no. 240 of 30 December 2010, may not be awarded to those who are in one or more of the following situations:

• those who have held contracts referred to in Article 24 of Law 240/2010;
• permanent staff, employed on a permanent basis, of universities, public research bodies and institutions whose scientific specialization diploma has been recognized as equivalent to the PhD pursuant to Article 74, fourth paragraph, of Presidential Decree no. 382 of 11 July 1980;
• those who have a degree of kinship or affinity, up to and including the fourth degree, with a professor or researcher belonging to the Department proposing the selection or with the Rector, the Director General or a member of the University's Board of Directors;
• have already benefited from Research Assignments referred to in Art. 22-ter of Law 240/2010 as amended by Law no. 79/2022 for a period which, added to the duration of the assignment provided for in the announcement, exceeds a total of 3 years, even if not continuous. For the purposes of the duration of the aforementioned relationships, periods spent on maternity or paternity leave or for health reasons according to current legislation are not relevant.

The total duration of relationships established with holders of positions referred to in Articles 22 - (Research Contracts), 22-bis (Post-doc Assignments), 22-ter (Research Assignments) and contracts referred to in Article 24 (RTT) of Law 240/2010, even with different universities, state, non-state or online, with institutions of higher artistic, musical and dance education, with institutions whose scientific specialization diploma has been recognized as equivalent to the PhD pursuant to Article 74, fourth paragraph, of Presidential Decree no. 382 of 11 July 1980, and with public research bodies may not in any case exceed 11 years, even if not continuous. For the purposes of the duration of the aforementioned relationships, periods spent on maternity or paternity leave or for health reasons according to current legislation are not relevant.

Candidates are admitted to the selection with reserve.

The Structure that issued the announcement may order at any time, by reasoned decree of the Director, the exclusion from the selection for lack of the required requisites.

Where to apply

Website: https://pica.cineca.it/

Requirements

• Research Field: Medical sciences » Medicine
• Education Level: Master Degree or equivalent

Work Location(s)

• Number of offers available: 1
• Company/Institute: Department of Medicine - University of Padova
• Country: Italy
• State/Province: Italy
• City: PADOVA, PD
• Postal Code: 35128
• Street: via Giustiniani, n. 2

Contact

• State/Province: Padova
• City: Padova
• Website: https://www.medicinadimed.unipd.it/
• Street: via Giustiniani, 2
• Postal Code: 35128