COI Project 1: Characterizing the ultrastructure of coronavirus replication complexes using in-situ cryo-Electron Tomography

About the Project

SARS-CoV-2 marked the third zoonotic insertion of a pandemic coronaviral infection into the human population, causing one of the greatest global health challenges to date. ... The aim of this project is to explore the fundamental aspects of sub-cellular compartmentalisation of coronaviral infection focusing on the structural composition of the replicase complex.