About the Center
The CCTCI is a newly established, interdisciplinary center dedicated to accelerating the discovery and clinical translation of next-generation immunotherapies, including first-in-human Phase I trials. The Center leverages UT Southwestern’s world-class infrastructure in cellular manufacturing, genomics, and early-phase clinical development to bridge bench and bedside.
Research Areas of Interest
We welcome applicants using cutting-edge tools to investigate and manipulate the immune system for therapeutic gain. Specific areas of interest include, but are not limited to:
- Machine learning applied to immunological challenges, such as modeling immune responses, antigen specificity, or cellular differentiation
- Protein engineering for immune modulation, including immune receptors, cytokines, and synthetic ligands
- Cellular engineering approaches, such as synthetic circuits, reprogramming, and in vivo cell targeting
- Genome engineering, including CRISPR-based systems, targeted epigenetic editing, and chromatin architecture manipulation for immunotherapy
Applicants working at the interface of computational, synthetic, and translational immunology are especially encouraged to apply.
Qualifications
- Ph.D., M.D., or equivalent degree in immunology, bioengineering, computational biology, or a related field
- A strong record of scientific innovation and productivity
- Demonstrated ability (or potential) to lead an independent, extramurally funded research program
- Commitment to interdisciplinary collaboration and mentorship
We are committed to building a diverse, equitable, and inclusive academic environment, and strongly encourage applications from individuals underrepresented in science and medicine.
Application Instructions
Interested candidates should submit the following materials:
- Cover letter
- Curriculum vitae
- 3-page research statement outlining past accomplishments and future directions
- Brief summary of up to three key publications (with links)
- Contact information for three referees
- Letters of recommendation (3)
Review of applications will begin September 1, 2026 and continue until December 31, 2026.
Equal Opportunity Employment Statement:
UT Southwestern Medical Center is an Equal Opportunity/Affirmative Action Employer. We encourage applications from qualified individuals regardless of race, color, religion, sex, national origin, disability, or protected veteran status.
Apply online at Interfolio: https://apply.interfolio.com/191483
Learn More
Explore the Choi Laboratory’s research, publications, and ongoing programs:
About UT Southwestern
UT Southwestern Medical Center is home to a vibrant and collaborative scientific community, including six Nobel Laureates, and over 80 members of the National Academies. We offer highly competitive startup packages, excellent benefits, and access to state-of-the-art core facilities and GMP infrastructure.
Learn more about UTSW employee benefits: https://www.utsouthwestern.edu/employees/hr-resources/
