Program Head, Phase I Clinical Trials

the University of Washington (UW) invite nominations and applications to lead the Phase I Developmental Therapeutics clinical trials program. The position will be dual appointed with a primary faculty appointment in the Clinical Research Division at Fred Hutch and a secondary appointment in the UW Department of Medicine, Division of Hematology and Oncology. The position will report to the Senior Vice President (SVP) of the Clinical Research Division at Fred Hutch and the Division Head of Hematology and Oncology at the UW. We seek a visionary leader to head our Phase I Developmental Therapeutics Program, focusing on innovative therapies to provide hope and healing to cancer patients. This Program Head will lead and oversee the development and execution of early-phase clinical trials for novel cancer therapies. This role is crucial in translating groundbreaking research into clinical practice, ensuring the safe and efficient evaluation of new treatments. The successful candidate will partner with leaders of the Fred Hutch immunotherapy integrated research center and cell-based therapy team to develop and execute an institutional early phase trial strategy. The Program Head will foster strong collaborations with translational researchers and clinical investigators at UW and Fred Hutch and will forge partnerships with biotech and pharmaceutical industry partners to grow the phase I program assets and advance our mission of delivering transformative cancer therapies to our patients. The Program Head’s overall responsibility will be to maintain and expand our Phase 1 clinical trials program in collaboration with our immune therapy and cell-based therapy teams. Specific tasks will include (1) providing leadership in designing, implementing, and managing early-phase clinical trials; (2) working on a team to oversee appropriate selection and placement of phase I trials (3) coordinating the infrastructure needed for optimal implementation of phase I studies, including research nurses, data coordinators, regulatory affairs, tissue acquisition, and biostatistical support; (4) working with medical oncology and other faculty to assure patient accrual to studies; (5) direct care of a portion of the study patients in addition to the faculty member’s standard of care patients; and (6) outreach to community oncology providers to enhance access to Phase 1 trials. The candidate may also specialize in the treatment of a cancer subtype, in which case they could maintain a subspecialty clinic that is separate from their role as the Phase I Program Head. The incumbent will serve as an academic, clinical and educational leader charged with organizing, directing and expanding the research efforts for an established team of clinical researchers involved in conducting phase I trials. Responsibilities include assisting with faculty recruitment as well as oversight and mentorship of faculty leading Phase I trials. Appointment at Fred Hutch would be at the rank of associate or full professor in the Clinical Research Division of the Fred Hutch. Appointment to the full-time faculty at the UW would be at the rank of associate or full professor. Academic appointments at the University of Washington will be commensurate with experience, qualifications, and academic rank. Associate and full professors hold indefinite appointments that both align with a 12-month service period (July 1-June 30). Faculty with 12-month service periods are paid for 11 months of service over a 12-month period (July-June), meaning the equivalent of one month is available for paid time off. Opportunities exist for joint and/or affiliate appointment in the Fred Hutch Divisions of Public Health Sciences, Translational Science and Therapeutics, Human Biology, Basic Sciences, or Vaccine and Infectious Disease, depending on mutual interests. Fred Hutch and University of Washington faculty engage in teaching, research, and service. The successful candidate will be appointed in the Clinician Scholar track and will spend approximately 30% of time on clinical care based on the candidate’s interests (and institutional need). The remainder of the incumbent’s time will be protected for research, administrative oversight of the Fred Hutch Phase I clinical research programs, teaching and mentorship, for the first three years, after which, the incumbent would be expected to cover at least half of their salary each year through grants, contracts, or clinical work. Strong candidates will demonstrate evidence of both leadership of Phase I research and clinical excellence. Faculty are expected to perform their primary activities on-site at Fred Hutch. Fred Hutch is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington. With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality. At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. This position is paid directly by Fred Hutchinson Cancer Center (Fred Hutch) and receives no UW compensation. Please refer to Fred Hutch for information about compensation for this position. Applicants must have: · MD/DO degree (or foreign equivalent) · Board certification in medical oncology (or foreign equivalent) · Eligibility for medical licensure in the state of Washington. In order to be eligible for sponsorship for an H-1B visa, graduates of foreign (non-U.S.) medical schools must show successful completion of all three steps of the U.S. Medical Licensing Exam (USMLE) or equivalent as determined by the Secretary of Health and Human Services. The ideal candidate will have a record of and primary interest in Phase I research, as demonstrated by peer-reviewed publications, grants and/or clinical trial experience. Interested candidates should submit the following: 1) Letter of interest addressed to the Chair of the Phase I Clinical Trials Program Head Search Advisory Committee, Dr. Gabi Chiorean 2) Curriculum vitae 3) One-page personal statement discussing research accomplishments, leadership experience, and outlining a vision for the growth and development of the Phase I program 4) List of five (5) references (References will not be contacted without first discussing this with the applicant). The annual base salary range for this position is from $394,718 to $423,138 for faculty hired at the Associate Professor rank, and from $456,089 to $513,101 for faculty hired at the Full Professor rank. Pay for Faculty positions is based on a variety of factors, including degree, specialty, clinical practice and experience. This position is eligible for relocation assistance or a sign-on bonus. Other compensation associated with this position may include an Administrative Supplement (ADS) in addition to base pay. Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (up to 13 days per year) and paid parental leave (up to 4 weeks). This position is not eligible for H-1B sponsorship at this time. We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to Human Resources at hrops@fredhutch.org or by calling 206-667-4700.