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Immune modulation of tonsillar Natural Killer cell immunity by Group A Streptococcus

Closes:

Salary: £21,805 per year

69

Summary

The human tonsils are crucial for producing neutralizing antibodies against infection yet are a breeding ground for Group A Streptococcus (GAS) which causes localized illnesses (tonsillitis) but also life threatening, invasive infections (>500,000 global deaths/year). Children prone to recurrent tonsillitis generate poor levels of neutralizing antibodies but the reasons why are unclear. Natural killer (NK) cells, immune cells that are typically protective, can suppress antibody production in…

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Cardiff University Jobs

Cardiff University

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