"Junior Specialist - McCormick lab"

The Helen Diller Family Comprehensive Cancer Center is seeking a full time Junior Specialist. The responsibilities for this position will include research involving tissue culture, molecular cloning, generation of knock out/-in cell lines using CRISPR-Cas9 techniques, protein interaction analysis, signal transduction pathway analysis, expression of recombinant proteins, preparation of samples for mass spectrometry analysis and possible mouse work. This position is for one year (with the possibility for renewal) and suitable for an individual with skills in biological sciences (preferred Biochemistry) who is looking to gain research experience on the way to further career development, such as going on to PhD training.

Areas of specialization include: development of high-throughput in vitro and in vivo plate-based assays such as ELISA and luminescent live-cell protein-protein interaction assays, and generation of enzymatic assays to understand regulation of GTPase activity; manipulation of these assays to screen chemical compounds for potential therapeutics.

Required Qualifications:

• Baccalaureate degree (or equivalent degree) or at least four years of research experience.
• Must have previous experience in laboratory work.
• Have strong analytical, organizational, and communication.
• Applicant must have all requirements met by time of hire.
• Applicant's materials must list (pending) qualifications upon submission.

Preferred Qualifications:

• Due to the nature of the position, it is preferred that the candidate have a strong Biochemistry background with prior experience performing biochemical enzymatic assays and plate-based assays.
• Some experience with chromatography systems is preferred e.g. FPLC or HPLC, or similar types of specialized lab equipment.
• The candidate should have knowledge of protein molecular structures and post-translational modifications, and be familiar with visualization and modeling.
• Useful skills include: tissue culture, electrophoresis, DNA manipulation techniques (molecular biology), western blotting, immunoprecipitation, protein purification, transfection and flow cytometry.

Appointees in the Specialist series will be expected to engage in specialized research, professional activities and do not have teaching responsibilities. Specialists are expected to use their professional expertise to make scientific and scholarly contributions, and may participate in University and Public Service. Screening of applicants will begin immediately and will continue as needed throughout the recruitment period. Salary and rank will be commensurate with the applicants experience and training.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $55,000 - $58,600.

Please apply online at https://aprecruit.ucsf.edu/JPF05785.

Document requirements

• Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).
• Cover Letter (Optional)
• Statement of Research (Optional)
• Statement of Teaching (Optional)

Reference requirements

• 2 letters of reference required