"Laboratory Science Professional"

Laboratory Science Professional

University of Colorado Anschutz Medical Campus

Department: Pharmacology / Functional Genomics Facility

Position #: 00839641 - Requisition #37911

Job Summary:

We are urgently hiring a skilled Lab Technician to ensure continuity and excellence in our Functional Genomics Facility following the departure of a key team member. This role is essential to maintaining core operations, supporting high-throughput workflows, and enabling cutting-edge research in gene function and regulation. The ideal candidate will be proficient in molecular biology techniques, sample processing, and data quality control, with a strong commitment to precision and reliability.

This position is vital to sustaining our research momentum and supporting collaborative projects across the institution. Join us to help drive impactful discoveries in functional genomics.

Key Responsibilities / Duties:

• Perform routine lab chores
• Generate relevant molecular reagents for more than 200 client labs across Colorado, which includes processing orders through iLabs, generating invoices, growing bacterial cultures, plasmid prep, maintaining HEK293FT for packaging viral particles, lentiviral and AAV prep, and managing order pick up.
• Skilled in using Microsoft Excel, Word, PowerPoint, SnapGene and R-studio
• Update website
• Help with reports and presentation preparation
• Give lab meeting (data or journal club)
• Assist with optimizing new protocols
• Custom RNAi and CRISPR panel design and cloning
• Adopt and adapt molecular biology tools to study gene function
• Contribute to the design and execution of collaborative projects that require the core facility's expertise

Experience in the following techniques will be viewed favorably:

• Bacterial culture, plasmid and genomic DNA isolation, gel electrophoresis, western blotting, end-point and real-time PCR, cell/tissue culture, mammalian cell transfection
• Knowledge of shRNA, ORF and CRISPR technology
• Library prep for Next Gen Sequencing
• Basic Bioinformatics and Computational Biology skills
• iPSC editing and analysis

Inventory, storage and management of lab specimens and reagents; associated record keeping

• Manage and update lab inventory of cell lines, reagents (media, serum, plasmids, etc.)
• Record keeping for customized projects
• Edited iPSC record keeping

Collaborate with researchers

• Design, execute and evaluate research investigations
• Literature reviews, performing experiments and pilots, data integration, and analysis

Foundational lab maintenance responsibilities

• Assist with various laboratory and clinical support operations, such as autoclaving, inventories, ordering supplies, and hazardous materials management.
• Prepare the lab for daily operations, including stocking materials, equipment, safety, cleanliness, and related areas

Work Location: Onsite - this role is expected to work onsite and is located in Aurora, CO

Why Join Us: Join the Functional Genomics Shared Resource (FGSR)-a leading core facility driving innovation in gene function research. We specialize in RNAi and CRISPR-based gene modulation, as well as protein and antibody engineering.

We're seeking motivated, detail-oriented Lab Science Professionals to support our iPSC team and daily operations. You'll contribute to impactful projects, perform functional assays, and help advance precision genomics.

Qualifications:

Minimum Qualifications:

• A bachelor's degree in biology, molecular biology, chemistry, genetics, or a directly related field from an accredited institution
• One (1) year of professional-level experience

Preferred Qualifications:

• A master's degree in biology, molecular biology, chemistry, genetics, or a directly related field from an accredited institution
• Two (2) years of professional-level experience.
• Individuals with advanced degrees and research experience are encouraged to apply
• Experience in RNAi and CRISPR technology
• Experience with pooled shRNA/CRISPR screening
• Experience with iPSC maintenance, differentiation, and experimentation
• Experience in independently researching, synthesizing, and presenting novel and assigned topics.
• Experience in training all ability levels (e.g., interns, colleagues) in sample processing procedures.

Competencies: Knowledge, Skills, and Abilities

• Ability to communicate effectively, both in writing and orally.
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.
• Ability to work with iPSC using established protocols.
• Flexibility and adaptability to schedule changes, including occasional night and weekend hours.
• Knowledge of aseptic technique and standard cell culture practices
• Must be hard-working, independent yet team-oriented, flexible, and able to communicate effectively.
• Self-motivated and highly organized, with demonstrated project planning and management skills in an academic research setting.
• Strong qualitative analysis skills and critical thinking
• Ability to manage the lab
• Demonstrated ability to plan, present, and conduct independent experiments.
• Willingness and working knowledge to assist the clinical research team and animal research team as needed.
• Familiarity with genomic, gene expression, proteomic, and metabolomic platforms.

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
2. Curriculum vitae / Resume
3. Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address

Questions should be directed to: Molishree Joshi, molishree.joshi@cuanschutz.edu

Anticipated Pay Range: HIRING RANGE ($50,357 - $64,054)