Laboratory Sciences Professional (Open Rank)

University of Colorado Anschutz

Department: Pediatrics, Section of Developmental Biology

Official Title: Laboratory Sciences Professional (Open Rank)

Position #: 00811014 – Requisition #: 39231

Job Summary:

The Zhu Laboratory at the University of Colorado Anschutz Medical Campus is seeking a highly motivated Research Services Professional to join a dynamic team focused on stem cell biology, regenerative medicine, and diabetes research. Our lab investigates how human pluripotent stem cells differentiate into pancreatic β-cells and applies cutting-edge tools—including CRISPR-based engineering, genomics, artificial intelligence–guided regulatory design, and functional metabolic assays—to develop next-generation cell therapies for type 1 diabetes.

This position offers the opportunity to contribute directly to high-impact translational research. The selected candidate will perform molecular and cellular experiments, support stem cell differentiation workflows, and assist in developing and optimizing functional assays that evaluate β-cell identity and performance. At the senior level, this role includes independent experimental planning, assay development, and active participation in data interpretation and research advancement.

Key Responsibilities:

• Perform basic molecular biology techniques, including buffer preparation, sample collection, RNA/DNA extraction, PCR, real-time qPCR, cloning, bacterial culture, mini-prep, sequencing, sample submission, gel electrophoresis, Western blotting, immunofluorescence staining, and fluorescence microscopy.
• Maintain laboratory organization, including receiving and logging reagents/products, tracking inventory, autoclaving materials, managing biological waste, and general laboratory upkeep.
• At the Senior level, perform mammalian cell culture, static and dynamic glucose-stimulated insulin secretion assays, luciferase/reporter assays, lentiviral production and transduction, and flow cytometry analysis after training.
• Accurately document experiments, organize data, and communicate results to the PI and lab team.
• Assist with laboratory protocols, SOP updates, and ordering supplies.
• Comply with all institutional guidelines for biosafety, chemical safety, and research integrity.

Work Location:

Onsite – this role is expected to work onsite and is located in Aurora, CO.