Life Science Research Professional 1

The Sheltzer Lab at Stanford University is seeking a Life Science Research Professional 1 for a cutting-edge project characterizing anti-cancer drug activity. Cancer cells require the expression of certain genes, called "addictions" or "genetic dependencies", that encode proteins necessary for tumor growth. Targeting the proteins encoded by these genes can trigger cell death and durable tumor regression. The Sheltzer Lab is applying CRISPR to study genetic dependencies in cancer in order to identify new therapeutic vulnerabilities and targets for drug development. Additionally, we are developing genomic approaches to investigate the on-target and off-target effects of different cancer drugs, with profound implications for their clinical use. The researcher will learn and apply multiple laboratory methods, including CRISPR-based gene targeting, cell culture, mouse husbandry, gel electrophoresis, western blotting, and flow cytometry, to investigate the biology of cancer. The successful candidate will have strong data analysis skills and will be comfortable performing as well as interpreting the results of laboratory experiments.

Duties include*:

• Plan experiments in support of research projects in the laboratory.
• Independently conduct experiments; maintain detailed records of experiments and outcomes.
• Analyze experiment results and offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
• Review literature on an ongoing basis to remain current with new procedures and directions.
• Contribute to publication of findings. Participate in the preparation of written documents, including procedures, presentations, and proposals.
• Help with general lab maintenance and support as agreed upon with supervising scientist.
• Onsite Work Agreement.

*- Other duties may also be assigned.

DESIRED QUALIFICATIONS:

The desired candidate should have experience in a chemistry, molecular biology, or biochemistry lab setting. A bachelor's degree in cell biology, molecular biology, biochemistry, chemistry, or biophysics is preferred. Candidates with at least one year of relevant experience and/or a master's degree or equivalent are preferred.

EDUCATION & EXPERIENCE (REQUIRED):

Bachelor's degree in related scientific field.

KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):

• General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
• Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
• Ability to maintain detailed records of experiments and outcomes.
• General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
• Ability to work under deadlines with general guidance.
• Excellent organizational skills and demonstrated ability to accurately complete detailed work.

PHYSICAL REQUIREMENTS*:

• Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
• Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
• Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
• Must have correctible vision to perform duties of the job.
• Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
• Ability to lift heavy objects weighing up to 50 pounds.
• Ability to work in a dusty, dirty, and odorous environment.
• Position may require repetitive motion.

*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

WORK STANDARDS:

• Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
• Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors bases on training and lessons learned.
• Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University's Administrative Guide, http://adminguide.stanford.edu.

The expected pay range for this position in the Stanford Work Location is $32.58 to $38.48 per hour.