Job Information
- Organisation/Company: INSERM
- Department: Centre Méditerranéen de Médecine Moléculaire
- Research Field: Medical sciences » Cancer research; Biological sciences » Biology
Offer Description
Context
Melanoma is a highly heterogeneous cancer characterized by a remarkable capacity to adapt to environmental and therapeutic constraints. Beyond genetic alterations, cellular architecture, nuclear organization and physical forces are increasingly recognized as important contributors to tumour cell behaviour and plasticity.
Internship project
The aim of this internship is to investigate how changes in nuclear morphology, nuclear organization and cellular mechanics are associated with melanoma cell plasticity and adaptation.
The student will work in an interdisciplinary research environment combining cancer biology, molecular and cellular biology, fluorescence microscopy and quantitative approaches.
Techniques and training
Depending on the progress of the project, the student will have the opportunity to gain experience in:
- melanoma cell culture and experimental cell biology,
- siRNA/shRNA-based gene modulation,
- real-time proliferation and viability assays,
- migration and invasion assays,
- fluorescence and confocal microscopy,
- immunofluorescence,
- quantitative analysis of cell and nuclear morphology,
- RNA extraction, RT-qPCR and Western blotting,
- chromatin-based approaches,
- quantitative image and data analysis.
Candidate profile
We are looking for a motivated Master 1 or Master 2 student with a background in cell biology, molecular biology, cancer biology or related life sciences. Curiosity, scientific rigour, autonomy and an interest in microscopy, quantitative biology and interdisciplinary research are particularly valued.
Location: C3M – Inserm U1065 / Université Côte d’Azur, Nice, France
Starting period: 2027, flexible according to the Master programme
Duration: according to the university programme
Supervisor: Dr Mickaël Ohanna
Application
Please provide a CV, short motivation letter, latest academic grades/transcript and class rank if available.
Where to apply
E-mail: michael.ohanna@inserm.fr
Requirements
- Research Field: Biological sciences » Biology
- Education Level: Bachelor Degree or equivalent
Skills/Qualifications
Strong interest in cancer biology, cell plasticity, nuclear architecture and quantitative biology. Basic knowledge of cell and molecular biology is expected. Previous experience in cell culture, fluorescence microscopy, molecular biology, image analysis or related experimental approaches would be appreciated but is not mandatory. Curiosity, scientific rigour, autonomy and willingness to learn new experimental and quantitative methods are particularly valued.
Specific Requirements
Current enrolment in a Master 1 or Master 2 programme in cell biology, molecular biology, cancer biology or related life sciences.
Applicants should provide a CV, a short motivation letter, their latest academic transcript/grades and class rank if available.
For Master 2 students, continuation toward a PhD may be considered depending on the progress of the project, the candidate’s performance and available funding
- Languages: ENGLISH — Level: Good
- Languages: FRENCH
- Research Field: Medical sciences » Cancer research; Biological sciences » Biology
- Years of Research Experience: None
Additional Information
Benefits
The student will join a multidisciplinary research environment combining cancer biology, molecular and cellular biology, advanced microscopy and quantitative approaches.
The internship will provide hands-on training in experimental and analytical methods and opportunities to interact with researchers from complementary disciplines.
The student will benefit from the scientific environment and technological platforms available at C3M and Université Côte d’Azur.
For Master 2 students, continuation toward a PhD may be considered depending on the progress of the project, the candidate’s performance and available funding.
Eligibility criteria
Applicants must be currently enrolled in a Master 1 or Master 2 programme in cell biology, molecular biology, cancer biology or a related life-science discipline.
A strong interest in cancer biology, cell plasticity, microscopy and quantitative approaches is expected.
Previous laboratory experience is appreciated but not mandatory.
Good working knowledge of English is required; French is not mandatory.
Selection process
Applications should include:
- a CV,
- a short motivation letter,
- the latest academic transcript/grades,
- class rank, if available.
Applications will be evaluated based on academic background, scientific motivation, previous research or laboratory experience, and fit with the project.
Shortlisted candidates will be invited for an interview.
Work Location(s)
- Number of offers available: 1
- Company/Institute: Centre Méditerranéen de Médecine Moléculaire (C3M) – Inserm U1065
- Country: France
- State/Province: alpes Maritimes
- City: Nice
- Postal Code: 06100
- Street: 151 route Saint Antoine de Ginestière
Contact
- State/Province: Provence-Alpes-Côte d’Azur
- City: Nice
- Website: https://www.inserm.fr/, https://www.c3m-nice.fr/
- Street: 28 Avenue Valrose
- Postal Code: 06100
- E-Mail: michael.ohanna@inserm.fr
- Phone: +33650986484
- Mobile Phone: +33650986484