Scientific summary
Intracellular transport pathways are fundamental for cell structure and function. Due to their longevity, complex morphology (long axonal and dendritic extensions) and requirement to maintain synaptic transmission, neurons are heavily dependent upon intracellular transport. Consistent with this, defects intracellular transport are directly linked to common forms of neurodegeneration. For example, altered function of the Rab activating protein C9orf72, a regulator of intracellular transport and…
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