Offer Description
We are seeking a highly motivated PhD student to join Inserm U1086 ANTICIPE at the François Baclesse Comprehensive Cancer Center in Caen, France. The PhD project will investigate the therapeutic potential of targeting UBE2N, a promising therapeutic target identified by our team, and its interplay with antitumor immunity in ovarian cancer. The project will combine cancer and molecular biology, pharmacology, immuno-oncology and patient-derived tumor organoid (PDTO) models to investigate treatment…
response and identify new therapeutic strategies. The PhD student will work in a multidisciplinary translational research environment, with access to the ORGAPRED tumor organoid core facility and expertise in DNA repair, pharmacology, precision oncology and tumor immunology. The position is for 36 months, with an expected starting date in January–February 2027.
Where to apply
E-mail: lb.weiswald@baclesse.unicancer.fr
Requirements
Research Field
Medical sciences » Cancer research
Education Level
Master Degree or equivalent
Skills/Qualifications
- Master's degree or equivalent degree recognized in France/the EU in cancer biology, molecular or cellular biology, pharmacology, immunology or a related discipline.
- Solid background in cancer biology and/or molecular and cellular biology.
- Knowledge of DNA repair.
- Knowledge of anticancer pharmacology and/or therapeutic combinations.
- Experience in mammalian cell culture.
- Experience with functional assays to assess treatment response is an advantage.
- Experience with patient-derived tumor organoids is an advantage.
- Good scientific English, both written and spoken.
- Ability to work independently while contributing effectively to a multidisciplinary research team.
Specific Requirements
- The candidate should demonstrate a strong interest in experimental cancer research and therapeutic development.
- Experience or knowledge in immuno-oncology, tumor–immune interactions or antitumor immune signaling would be considered a strong advantage.
- Previous experience with animal experimentation is not mandatory but would be an asset.
- The candidate should be motivated to develop new experimental skills and progressively acquire autonomy in project design, experimental work, data analysis and scientific communication.
Languages
ENGLISH
Level
Excellent
Additional Information
Benefits
- 36-month PhD position within a multidisciplinary Inserm research unit.
- Research conducted at the François Baclesse Comprehensive Cancer Center, a leading comprehensive cancer center in Normandy.
- Access to the ORGAPRED tumor organoid core facility and advanced patient-derived tumor models.
- Interaction with researchers, clinicians and technical experts in translational cancer research.
- Training in multidisciplinary approaches combining cancer biology, pharmacology, molecular biology, immuno-oncology and precision oncology.
- Opportunities to present research at national and international scientific conferences and contribute to scientific publications.
- A stimulating international and collaborative research environment in Caen, Normandy, France.
Eligibility criteria
- Applicants must hold a Master's degree or equivalent qualification allowing enrolment in a doctoral programme in France, preferably in cancer biology, molecular/cellular biology, pharmacology, immunology or a related discipline.
- International candidates are welcome to apply, provided that their academic qualifications are recognized as equivalent for doctoral enrolment in France.
Selection process
The application should include a CV, master's degree transcripts / academic records, one reference letter or the contact details of one academic or research referee, and brief motivation for joining the U-STING project and explain how the candidate's academic background and research experience relate to the proposed research. Interested candidates should send their application by email to both supervisors:
Dr. Louis-Bastien Weiswald
Inserm U1086 ANTICIPE – François Baclesse Cancer Center
lb.weiswald@baclesse.unicancer.fr
Dr. Matthieu Meryet-Figuière
Inserm U1086 ANTICIPE – François Baclesse Cancer Center
m.meryet-figuiere@baclesse.unicancer.fr
Applications will be reviewed by the project supervisors and members of the research team.
Shortlisted candidates will be invited for an interview, which may be conducted remotely for international applicants.
The selection process will consider:
-academic background and research experience;
-technical skills relevant to the project;
-scientific motivation and interest in cancer research;
-ability to work in a multidisciplinary environment;
-communication skills and potential for scientific development.
Additional comments
Expected starting date: January–February 2027.
Work Location(s)
Number of offers available
1
Company/Institute
Université de Caen Normandie - François Baclesse Comprehensive Cancer Center
Country
France
City
Caen
Postal Code
14076
Street
3 avenue du général Harris
Contact
City
Caen
Website
http://www.unicaen.fr
Street
Esplanade de la Paix 14032 CAEN CEDEX
Postal Code
CS 14032
E-Mail
lb.weiswald@baclesse.unicancer.fr