Plant immunity relies on pattern recognition receptors (PRRs) for the detection of invading pathogens, with leucine-rich repeat receptor-like proteins (LRR-RLPs) representing one of the most diverse receptor families. The overarching goal of our project, REVALUTION, is to re-evaluate ambiguous ligand–receptor interactions in an evolutionary framework. In close collaboration with the Koch/Walden group at the Centre for Organismal Studies (COS), Heidelberg, the project explores how genome evolution drives the diversification of plant immune receptors and their capacity to recognize diverse pathogen-derived molecules, using the Arabidopsis receptor RLP30 and the Nicotiana receptor RE02 as model systems (Yang et al., 2023, Nature Communications; Yang et al., 2025, Nature Biotechnology).
The successful candidate will join the research groups of Laura Medina-Puche and Andrea Gust at the ZMBP. The project combines evolutionary genomics, AI-guided structural modelling, and molecular and functional biology to discover novel Brassica immune receptors and unravel the molecular principles governing ligand recognition and downstream signalling in RLP30/RE02-like receptors.
We are seeking an enthusiastic and highly motivated graduate with an excellent Master's degree in Biology, Biochemistry, or a related discipline. The ideal candidate has a strong interest in plant immunity and evolution, is proficient in English, and has practical experience in plant molecular biology, biochemistry, genetics, and microscopy.
The successful applicant will benefit from:
- A stimulating, collaborative, and supportive international research environment.
- Integration into the interdisciplinary GreenRobust research network.
- Access to state-of-the-art research infrastructure and facilities.
- Opportunities for scientific and professional development through mentoring and career training.
- Tübingen as a vibrant university town offering an exceptional quality of life in a beautiful historic setting.
The University of Tübingen is committed to equal opportunities and diversity and actively promotes gender equality. The University aims to increase the proportion of women in research and teaching and therefore particularly encourages qualified women scientists to apply. Severely disabled applicants will be given preference in the case of equal qualification.
Please submit your application as a single PDF file containing:
- a cover letter,
- a summary of your previous research experience,
- a curriculum vitae,
- certificates, and
- the contact details of two academic referees.
Applications should be sent by 9th October 2026 via email to Dr. Andrea Gust andrea.gust@zmbp.uni-tuebingen.de or Dr. Laura Medina-Puche laura.medina-puche@zmbp.uni-tuebingen.de.
The appointment will be made by the Central Administration (Zentrale Verwaltung).
