PhD Position

Is the Job related to staff position within a Research Infrastructure? No

Offer Description

We are looking for an outstanding and highly motivated PhD candidate to join the RESTORE project at the Institut reConnect, Institut Pasteur in Paris.

The project will develop next-generation AAV gene therapy and precision genome editing for Usher syndrome, building on unique humanized mouse models and strong in vivo proof-of-concept data. The successful candidate will investigate how therapeutic efficacy, intervention timing and long-term safety determine functional rescue of the inner ear.

This PhD offers multidisciplinary training at the interface of gene therapy, CRISPR-based genome editing, sensory neuroscience, advanced imaging and in vivo functional phenotyping, within an internationally recognized research environment.

We particularly encourage applications from ambitious young scientists with an excellent academic record and a background in molecular/cell biology, neuroscience, genetics or biotechnology. Prior expertise in gene therapy or genome editing is an advantage, but scientific curiosity, rigor and the drive to tackle challenging biomedical questions matter most.

From patient mutation → to genetic correction → to restored sensory function.

Interested in developing tomorrow’s precision therapies for inherited hearing disorders?

Apply to : aziz.el-amraoui@pasteur.fr & sandrine.vitry@pasteur.fr

& via website: https://ppu.pasteur.fr/ppu_etud_accueil.aspx

Where to apply

Website: https://ppu.pasteur.fr/ppu_etud_accueil.aspx

Requirements

Research Field: Other

Education Level: Master Degree or equivalent

Skills/Qualifications

We are seeking an outstanding and highly motivated candidate with an excellent academic record and a strong interest in translational biomedical research. Applicants should hold a non-French master’s degree in molecular or cellular biology, neuroscience, genetics, biotechnology, or a related discipline.

Specific Requirements

Previous research experience in molecular biology, cell biology, or animal models is expected. Experience with gene therapy, genome editing, or advanced imaging will be considered an advantage but is not mandatory. We are looking for a curious, rigorous, and creative young scientist eager to contribute to innovative therapeutic approaches and to develop an international research career.

Additional Information

Work Location(s)

Number of offers available: 1

Company/Institute: Institut Pasteur

Country: France

City: Paris

Contact

City: Paris

Website: http://www.pasteur.fr https://research.pasteur.fr/en/team/progressive-sensory-disorders-pathophysiology-and-therapy/

Street: 25, rue du Dr Roux, 75015 Paris