"PhD student: Platelet (phospho)proteomes in health and disease"

Job Summary

We are looking for a PhD student to join the mission of the Medical Priority Bleeding & Hemostasis of Sanquin Research to improve diagnosis and treatment of patients suffering from acquired and congenital bleeding disorders. Platelets are essential for primary hemostasis and dysfunctionality is associated with hemostatic disorders, including bleeding and thrombosis. In this PhD project, we aim to advance our molecular understanding of platelet biology through integrated complementary mass spectrometry-based approaches, including (phospho)proteomics, peptidomics, and metabolomics. In addition, we will relate platelet signaling mechanisms to genetic background and (rare) disease. We especially encourage applications of talented researchers with the skills and ambition to integrate ‘omics’-based profiling data with the ultimate goal to identify and study novel pathogenic mechanisms underlying platelet (dys)function.

Responsibilities

The PhD student will employ a variety of proteomics and bio-informatics approaches to address platelet biology, work efficiently independently, and collaborate closely with a multidisciplinary and international team.

Qualifications and Requirements

A MSc degree in (systems) biology and/or (bio)molecular/biomedical/pharmaceutical/bio-analytical sciences or equivalent. Pro-active and eager to learn; good communication skills in English; the ability to work efficiently independently and in close collaboration with a multidisciplinary and international team composed of highly ambitious young researchers.

What the Employer Offers

We offer unique research opportunities in a dynamic environment. Salary and working conditions conform to CAO Sanquin. Temporary position for the duration of 4 years (PhD student); a full-time contract of 36 hours per week; 8.33% end-of-year bonus; 8.33% holiday allowance; partial reimbursement of travel expenses; pension plan with Pensioenfonds Zorg & Welzijn (PFZW), Sanquin contributes 65%; collective discounts on various insurances; at full-time employment (36 hours) 201 hours of leave per annum.