Post-Doc Positions for Deciphering Principles & Mechanisms of the Zygotene Cilium: A Newly Identified Cilium in Developing Oocytes

Location: Ein Kerem Campus, Jerusalem, Israel

About Our Research: The Elkouby Lab (https://www.yanivelkoubylab.com/) studies how eggs are produced, focusing on early oogenesis, from the germline stem cell to the primary follicle. This ERC-funded project investigates the newly discovered zygotene cilium—a previously unrecognized cilium essential for meiotic chromosomal pairing and germ cell morphogenesis. The Lab has established its presence in both zebrafish and mice, revealing its vital role in ovary development and fertility. The position offers a unique opportunity to explore ciliary mechanics, developmental signaling, and reproductive biology using cutting-edge live imaging, genetic manipulation, and deep-learning image analysis. The research also investigates how findings translate to understanding human ciliopathic proteins.

Job Description: We are seeking two highly motivated and talented post-doctoral researchers to join our international team. The postdocs will participate in a team effort aimed at deciphering the mechanical, functional, and regulatory components of the zygotene cilium. Responsibilities include performing advanced imaging, genetic manipulation in zebrafish, and molecular analyses. Opportunities exist for involvement in single-cell transcriptomics, proteomics, and developmental modeling. The Elkouby Lab provides a collaborative environment, access to state-of-the-art microscopy, and a long-term ovary culture system for live imaging.

About Your Supervisor: Prof. Yaniv Elkouby leads the Elkouby Lab at the Hebrew University of Jerusalem. His research focuses on novel cellular and developmental mechanisms in early oogenesis. He has pioneered whole-ovary live imaging approaches, integrating quantitative microscopy, deep learning, and functional manipulation techniques. Prof. Elkouby's work has led to major breakthroughs in the understanding of oocyte development, including the discovery of the zygotene cilium and symmetry-breaking mechanisms in oogenesis. He directs a talented team of international researchers, and his lab is equipped with cutting-edge tools and imaging facilities.

Funding: Annual fellowship of $38,000–42,000 (NIS equivalent), funded by the European Research Council (ERC).

Your Profile:

• A PhD in life sciences (cell/developmental biology or related fields)
• Strong background in developmental biology
• Expertise in zebrafish research, genetics, and transgenesis
• Excellent communication skills in English

Advantages:

• Molecular biology skills; microscopy and imaging experience is an advantage
• Experience in single-cell transcriptomics or proteomics is a plus

Application: Please submit the following documentation as three separate PDF files:

• Letter of motivation
• CV (including a list of publications)
• Copy of your original academic degree(s)

Application Deadline: 2026-03-16 23:59 (Asia/Jerusalem)