"Post-Doc Research Associate"

Job Details

Department: Lineberger Compr Cancer Center - 426801

Posting Open Date: 01/24/2024

Application Deadline: 02/02/2024

Open Until Filled: Yes

Position Type: Postdoctoral Scholar

Position Title: Post-Doc Research Associate

Vacancy ID: PDS004087

Full-time/Part-time: Full-Time Temporary

Hours per week: 40

FTE: 1

Work Location: Chapel Hill, NC

Position Location: North Carolina, US

Hiring Range: Dependent on Education/Experience

Estimated Duration of Appointment: 12 Months

Be a Tar Heel!: A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation’s top public universities and is among is the top ten research universities in the nation for federal research expenditures as well as for federally funded social and behavioral sciences research and development. Here at Carolina, our highly skilled postdocs play a vital role in our research enterprise and towards our overall commitment to research excellence. Across many disciplines, postdocs contribute to the intellectual vitality of the University. They provide innovative ideas and perspectives, foster a stimulating research environment and advance knowledge within their fields. Postdocs are crucial members of our scientific research workforce, contributors to our research outputs and an important reason why Carolina is one of the leading public research institutions in the country. UNC-Chapel Hill offers postdocs comprehensive medical and vision coverage, paid leave, and benefits and services that support professional development and a healthy work/life balance. Chapel Hill regularly ranks as one of the best college towns and best places to live in the United States, a reputation guided by the diverse social, cultural, recreation and professional opportunities that span the campus and community.

Primary Purpose of Organizational Unit: The UNC School of Medicine has a rich tradition of excellence and care. Our mission is to improve the health and wellbeing of North Carolinians, and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. We strive to promote faculty, staff, and learner development in a diverse, respectful environment where our colleagues demonstrate professionalism, enhance learning, and create personal and professional sustainability. We optimize our partnership with the UNC Health System through close collaboration and commitment to service. Our vision is to be the nation’s leading public school of medicine. We are ranked 2nd in primary care education among all US schools of medicine and 5th among public peers in NIH research funding. Our Allied Health Department is home to five top-ranked divisions, and we are home to 18 top-ranked clinical and basic science departments in NIH research funding. Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. Patient Care: We will promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond. Education: We will prepare tomorrow’s health care professionals and biomedical researchers by facilitating learning within innovative curricula and team-oriented interprofessional education. We will cultivate outstanding teaching and research faculty, and we will recruit outstanding students and trainees from highly diverse backgrounds to create a socially responsible, highly skilled workforce. Research: We will develop and support a rich array of outstanding health sciences research programs, centers, and resources. We will provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our University to support outstanding research. We will foster programs in the areas of basic, translational, mechanistic, and population research.

Position Summary: One postdoctoral associate position is available in a cancer research lab located within the University of North Carolina at Chapel Hill Lineberger Cancer Center. The lab currently studies the hypoxia signaling, prolyl hydroxylases, and cancer, specifically breast and renal cell carcinoma. One project focuses on using novel proteomic and genomic approaches to screen for novel prolyl hydroxylase substrates that play important roles in various of cancer. The other project involves integrating ChIP-seq strategy with gene expression profiling to identify EglN2 prolyl hydroxylase and Hypoxia-inducible factor 1 (HIF1) targets in the malignant diseases. The ultimate goal is to understand mechanistically how oxygen-sensing pathways contribute to cancer progression, which will facilitate our design of an effective treatment strategy to target cancer specifically. Besides these major research directions, we are also interested in studying the mechanism of chromosomal instability in cancer, specifically related to FBW7 tumor suppressor pathways.

Minimum Education and Experience Requirements: Ph.D. in a Biology related field such as biochemistry, molecular/cell biology, or cancer biology

Required Qualifications, Competencies, and Experience: Ph.D. in a Biology related field such as biochemistry, molecular/cell biology, or cancer biology

Preferred Qualifications, Competencies, and Experience: Strong background in molecular/cell biology, biochemistry, and cancer biology.

Special Instructions: For information on UNC Postdoctoral Benefits and Services click here