Few medical therapies are available for patients with small bowel neuroendocrine tumors (SBNETs) and the existing options are not very effective at eliminating the cancer. Our goal is to investigate the mechanism of drug resistance in SBNETs. We aim to determine the expression of NRF2 in SBNET tissue microarrays in comparison to other NETs. We will genetically modulate NRF2 activity by performing NRF2 and KEAP1 Knockout and test for drug sensitivity in vitro and in vivo models. In addition, we will characterize the interaction between NRF2 and its binding partner in patient-derived SBNET spheroids.

JOB DESCRIPTION:

• Helps design and conduct research within a specified field while receiving advanced training from a designated Principal Investigator to enhance professional skills and research independence needed for pursuit of a career.
• The specific area of research in which the trainee is mentored is determined by the department and laboratory of the Postdoc.
• Designs and evaluates experiments.
• Develops new ideas that promote current research.
• Prepares and publishes scientific manuscripts under the direction of the Principal Investigator.
• May be responsible for operation of specific equipment.
• May teach techniques to others, train, and supervise research staff.
• Positions are temporary appointments as a research trainee.
• The initial appointment is for one year, renewal expected if progress is satisfactory and funds are available.
• Appointments cannot exceed five years.

MINIMUM QUALIFICATIONS:

• A doctoral degree or equivalent (Ph.D., M.D., ScD., D.V.M., DDS etc) in an appropriate field.
• Excellent scientific writing ability and strong oral communication skills.
• The ability to work effectively and collegially with colleagues.
• Additional qualifications as specified by the Principal Investigator.

NOTE: Position tasks are required to be performed in-person at an Emory University location; working remote is not an option. Emory reserves the right to change this status with notice to employee.