Position Summary

The Wells Lab, in the Complex Carbohydrate Research Center at the University of Georgia, is seeking a motivated Biochemist/Cell Biologist to explore the O-Mannose pathway and its role in Congenital Muscular Dystrophy (CMD). This position is part of a robust research program funded by the NIH, NSF (BioFoundry), and the Michael J. Fox Foundation. You will bridge glycobiology and functional genomics, focusing on how defective O-mannosylation leads to muscle and neural phenotypes in a highly collaborative, well-funded environment.

Duties/Responsibilities

• Design and execute high-throughput genetic screens to identify novel modifiers of O-mannosylation. (25%)
• Utilize CRISPR/Cas9 for cell line creation and genomic editing including establishing and characterizing muscle and neural cell lines (including iPSCs). (25%)
• Characterize disease mechanisms using advanced imaging and functional assays. (20%)
• Purify and characterize enzyme variants associated with CMD. (15%)
• Present and publish findings. (10%)
• Grant writing (5%)

Relevant/Preferred Education, Experience, Licensure, Certification

• Ph.D. in Biochemistry, Cell Biology, or a related discipline.
• Extensive experience in high-throughput screening and cell line engineering.
• Strong background in characterizing muscle and/or neuronal development/signaling.