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Postdoctoral Associate, Bathe Lab

Postdoctoral Associate

2026-09-26

Type

Full-time

Required Qualifications

Ph.D. in biomedical engineering, cell biology, molecular biology or related

Mammalian cell culture experience

Multiplexed protein or RNA detection methods

Quantitative data or image analysis

Research Areas

Synaptomics

Neuroscience

iPSC-derived neurons

Drug screening

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Posting Description

POSTDOCTORAL ASSOCIATE , Bathe Lab, to work on PRISM (Probe-based Imaging for Sequential Multiplexing), a multimodal synaptomics platform developed in the lab that simultaneously measures synaptic protein composition, local mRNA translation, and synaptic activity at single-synapse resolution. This is an exciting opportunity to help answer fundamental questions about how neuropsychiatric diseases such as schizophrenia and autism manifest at the synapse in human neurons, and whether those changes…

can be pharmacologically reversed. The postdoc will play a central role in extending PRISM into human iPSC-derived neurons for scalable, automated drug screening. Core responsibilities span neuronal cell culture, multiplexed imaging assay development, automation of liquid-handling and imaging workflows, and computational analysis of high-content synaptic datasets. The position sits at the intersection of technology development, translational neuroscience, and drug discovery.

Job Requirements

REQUIRED: Ph.D. in biomedical engineering, cell biology, molecular biology, or a related field; and experience with mammalian cell culture, multiplexed protein or RNA detection methods, and quantitative data or image analysis. PREFERRED: Experience with high-content imaging, automated screening platforms, or computational image analysis pipelines.

7/14/2026

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Postdoctoral Associate, Bathe Lab

MIT - Massachusetts Institute of Technology

77 Massachusetts Ave, Cambridge, MA 02139, USA