Job Description Required Qualifications: (as evidenced from an attached resume Doctoral degree (or foreign equivalent) in Biology, Medicine or a closely related field in hand by the start of the appointment. Have at least one first-author original publication in a highly regarded peer-reviewed journal in the field of cancer, cardiovascular disease, or immunology research. Preferred Qualification: Laboratory research experience with hematopoietic stem cell biology, cardiovascular diseases, and…
immunology. Job Description: The Zhan Lab is seeking highly motivated individuals to join our research team investigating hematopoietic stem cell biology, myeloproliferative neoplasms (MPNs), clonal hematopoiesis, and cardiovascular disease. Our research focuses on understanding how hematopoietic mutations interact with the bone marrow microenvironment to drive clonal expansion and disease progression, with a particular emphasis on the JAK2V617F mutation. Using genetically engineered mouse models, transplantation studies, and molecular and cellular approaches, we investigate how the hematopoietic stem cell (HSC) niche--particularly megakaryocytes and vascular endothelial cells--regulates mutant HSC expansion and persistence. We also study competition between normal and mutant HSCs, with the goal of identifying mechanisms that enhance normal HSC fitness and suppress mutant clonal expansion. A major area of the laboratory's research examines the mechanisms linking JAK2V617F-mutant hematopoiesis to cardiovascular disease, including thrombosis, vascular dysfunction, and cardiac disease. Our work integrates stem cell biology, vascular biology, clonal hematopoiesis, and cardiovascular research to identify novel disease mechanisms and potential therapeutic strategies for MPNs and their cardiovascular complications. The Postdoctoral Associate will support basic science and pre-clinical research. The ideal candidate shall possess strong scientific and technical skills, critical thinking ability, and a thoughtful approach to troubleshooting. A strong work ethic, resilience, and motivation are essential, along with openness to developing a research niche that complements ongoing projects. Excellent written and verbal communication skills are also required. Specific Duties: * Plan experiments and technical requirements, prepare and test specimens. * Analyze data and present the results at various scientific meetings, prepare the manuscripts and grants. * Maintains laboratory equipment/supplies/facilities. Execute the administrative aspects of the study plan including preparing research-related documents. * Other duties as assigned. Special Notes: The Research Foundation of SUNY is a private educational corporation. Employment is subject to the Research Foundation policies and procedures, sponsor guidelines and the availability of funding. FLSA Exempt position, not eligible for the overtime provisions of the FLSA. Minimum salary threshold must be met to maintain FLSA exemption. Visit The Office of Postdoctoral Affairs to learn more about our postdoctoral community. Resume/CV and cover letter should be included with the online application. Stony Brook University is committed to excellence in diversity and the creation of an inclusive learning, and working environment. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, familial status, sexual orientation, gender identity or expression, age, disability, genetic information, veteran status and all other protected classes under federal or state laws. If you need a disability-related accommodation, please call the university Office of Equity and Access (OEA) at (631) 632-6280 or visit OEA . In accordance with the Title II Crime Awareness and Security Act a copy of our crime statistics can be viewed here . Visit our WHY WORK HERE page to learn about the total rewards we offer. SUNY Research Foundation: A Great Place to Work. The starting salary range (or hiring range) to be offered for this position is noted below, it represents SBU's good faith and reasonable estimate of the range of possible compensation at the time of posting. Job:Post Doctoral

