Unit: College of Humanities and Sciences
Department : School of Life Sciences and
Sustainability
Position Summary/Overview:
The Ehrlich Lab in the Department of Developmental, Cellular and
Molecular Biology at Virginia Commonwealth University is seeking a
highly motivated Postdoctoral Fellow with expertise in cell
signaling, trafficking, cell culture and fluorescence microscopy to
join our research team. Our lab investigates the cellular and
molecular mechanisms underlying psychiatric and substance use
disorders, using mammalian cell and neuronal culture models
combined with quantitative imaging and biochemical approaches to
study how drugs of abuse affect cell biology and neuronal function.
This is an excellent opportunity for an early-career scientist to
lead independent research projects, contribute to high-impact
publications, and gain mentorship in a collaborative,
well-resourced environment. To apply, please submit a
curriculum-vitae (CV), cover letter, and name and contact
information for three references through VCU Jobs.
This is a one
year position, renewable for up to three years contingent on
performance and funding.
The Ehrlich lab has just been established and offers the candidate
an environment to learn how to set up a research lab as well as a
prominent role in mentoring junior trainees. The successful
candidate is expected to obtain fellowship funding within the first
2 years. The lab has recently been awarded National Institute on
Drug Abuse (NIDA) funding to follow-up our exciting findings. (
https://pubmed.ncbi.nlm.nih.gov/38678559/)
that discovered the analgesic morphine activated mu opioid receptor
localizes and traffics to the neuronal primary cilium. This
foundational work is opening the door to an entirely new area of
opioid research which may have far-reaching impact on areas
including addiction and pain. Our work is funded by NIDA and
combines mammalian cell culture, neuronal/neuroscience-relevant
model systems, quantitative fluorescence microscopy, and
biochemical approaches to dissect the cellular pathways underlying
opioid action at the molecular level. VCU is a top-tier research
university located in Richmond, Virginia, with strong core
facilities in genomics, microscopy, and flow cytometry, and a
vibrant, collaborative biomedical research community.
NOTE: The successful candidate understands that this is a
restricted position and ongoing employment depends on continued
funding.
Position Responsibilities:
- General lab operation and maintenance in a mammalian cell
biology lab.
- Design and execution of independent experiments within the
lab's broader research program including generating primary
neuronal cultures from rodents.
Maintenance and manipulation of mammalian cell lines, including
transfection, electroporation and generation of stable/mutant cell
lines.
Assessment of cellular phenotypes via localization,
quantitative fluorescence microscopy, and biochemical
approaches.
Data processing, analysis, and preparation of figures for
presentation and publication.
Presentation of data and findings at university and
national-level events and symposiums
Training and mentoring of graduate and undergraduate
students.
Grantsmanship training will be acquired through postdoctoral
fellowship applications
Contribute to grant writing and lab administrative tasks as
needed.
Maintain accurate records and ensure compliance with
institutional and regulatory guidelines.
Qualifications:
Minimum Qualifications
- PhD (or expected completion by start date) in Life Sciences,
Cell Biology, Molecular Biology, Biochemistry, or a related
field.
- Knowledgeable about vesicular endocytosis and trafficking
machinery • Background or interest in mechanistic experimental
design
- Extensive hands-on experience with mammalian cell culture or
relevant model system, including maintenance, passaging, and
transfection of cell lines
- Proficiency in quantitative fluorescence microscopy and
biological image analysis (e.g., ImageJ)
- Proficiency in general cell biology and biochemistry
techniques, including DNA gel electrophoresis, SDS-PAGE/Western
blotting, protein purification, and protein-protein interaction
assays (e.g., pulldowns)
- Statistical analysis skills (e.g., GraphPad Prism) and general
data processing/analysis
- Strong written and verbal communication skills, including
scientific writing and public presentation
- Demonstrated research productivity (minimum 2 first-author
peer-reviewed publications)
- Ability to work both independently and collaboratively in a
team environment
- Demonstrated ability to work in and foster an environment of
respect, professionalism and civility with a population of faculty,
staff, and students from all backgrounds and experiences, or a
commitment to do so as a staff member at VCU.
Preferred Qualifications
- Experience with neuronal cell culture or other
neuroscience-relevant model systems.
- Experience with molecular cloning and PCR-based genetic
editing.
- Experience with scientific graphic design (e.g., Adobe
Photoshop, biorender, Illustrator) for figure preparation.
- Prior experience training and mentoring graduate or
undergraduate students • Strong project planning and management
skills.
Benefits: All full-time university staff are eligible for
VCU’s robust
benefits
package that includes comprehensive health benefits, paid annual
and holiday leave granted up front, generous tuition benefits,
retirement planning and savings options, tax-deferred annuity and
cash match programs, employee discounts, well-being resources,
abundant opportunities for career development and advancement, and
more.
Salary: $55,000-$65,000
Restricted: Yes
FLSA Exemption Status : Exempt
Hours per Week: 40
ORP Eligible: Yes
Contact Information:
Contact Name: Aliza
Ehrlich
Contact Email: ehrlicha@vcu.edu