Postdoctoral Fellow in Biophysics

About the Department

The Department of Biochemistry and Biophysics. SciLifeLab is a national center for molecular biosciences with focus on health and environmental research. The center combines frontline technical expertise with advanced knowledge of translational medicine and molecular bioscience.

SciLifeLab is a national resource hosted by:

• Karolinska Institutet
• KTH Royal Institute of Technology
• Stockholm University
• Uppsala University

The employment will be placed at the Department of Biochemistry and Biophysics at Stockholm University.

Project Description

A postdoctoral position is available in the research lab of Emil Marklund, based at SciLifeLab campus Solna in Stockholm.

In the Marklund lab, researchers investigate how sequence information in biological macromolecules governs recognition, binding, and dynamical structure. The lab combines high-throughput measurements of molecular binding with simulations and quantitative modeling to gain a physical understanding of life at the molecular level.

The lab is recruiting a Postdoc interested in using and developing state-of-the-art methods for studying binding and dynamical structure of DNA, RNA, and proteins.

Main Responsibilities

The candidate will use and develop methods within one or multiple of the following categories:

Optical Engineering, Fluorescence Microscopy, and Image Analysis

Development of microscopes, fluidics, and data analysis pipelines used to acquire and quantify high-throughput binding data.

Sequence Library Design, Molecular Cloning, and Protein Purification

Designing and preparing molecular sequence variants for which binding is to be studied in high-throughput.

Building Quantitative Models

Using high-throughput binding data to build sequence-dependent predictive deep learning models or physical mechanistic models.

Qualification Requirements

To qualify for a Postdoctoral position, applicants are required to hold a Swedish doctoral degree or an equivalent relevant degree from another country. The degree must have been completed no later than when the employment decision is made.

Assessment Criteria

It is considered an advantage if the doctoral degree or equivalent degree was completed no more than three years prior to the application deadline. Special attention will be given to research skills in biophysics, molecular biology, biochemistry, optical engineering, and deep learning.

About the Employment

Type of employment: Temporary position. Contract type: Full time. Duration: Minimum two years and maximum three years. Start date: As per agreement.