Job Description Summary

The Lukesh Research Group in the Department of Chemistry at Wake Forest University invites applications for a postdoctoral research position in organic chemistry and chemical biology. The successful candidate will work closely with Prof. John Lukesh (https://lukeshjc.sites.wfu.edu) on the design, synthesis, and evaluation of small-molecule donors (prodrugs) and reaction-based sensors to investigate the chemical biology and therapeutic potential of reactive sulfur and selenium species. Candidates should have a strong background in multistep organic synthesis and a willingness to apply a range of analytical, biochemical, and cell-based techniques. Experience with mammalian cell culture and cellular functional assays is desirable. The ideal candidate will be highly motivated, collaborative, and interested in working at the interface of chemistry and biology.

This position is available on a one-year contractual basis, with the possibility of extension based on performance and funding availability.

Job Description

This position is not eligible for sponsorship of non-immigrant or immigrant visa status through Wake Forest University. All eligible applicants are encouraged to apply.

Essential Functions:

• Design, synthesize, and characterize small molecules through multistep organic synthesis.
• Investigate the chemical, photophysical, and biological properties of target compounds using a variety of analytical and biochemical techniques.
• Contribute creative ideas that advance ongoing research programs and foster new research directions.
• Mentor and provide technical training to undergraduate and graduate researchers.
• Maintain accurate, detailed, and organized research records, including laboratory notebooks and electronic data files.
• Adhere to and promote a safe laboratory environment in accordance with university and departmental policies.
• Analyze and interpret experimental data and communicate findings effectively.
• Prepare manuscripts for publication in peer-reviewed scientific journals and contribute to grant writing activities as appropriate.

Required Education, Knowledge, Skills, Abilities:

• Ph.D in chemistry or a related area, or an equivalent combination of education and experience.
• Training and experience with modern synthetic organic chemistry (including air and water sensitive reagents), modern chromatography and spectroscopic methods or training and experience in biochemical assays, molecular biology and/or cell culture techniques.
• Skilled in the safe and accurate use of chemical reagents.
• Strong communication (verbal and written) skills.
• Ability to work effectively in a group as part of a team.
• Proficiency in the use of computers including spreadsheets, safety training and online ordering.
• Ability to work with minimal supervision.
• Moderate physical activity.

Preferred Education, Knowledge, Skills, Abilities:

• Research background in synthetic organic chemistry and/or chemical biology.