"Postdoctoral Research Scholar"

Job Details

Posting Number: PG191545PD

Position Number: 00111581

Position Type: Post Doc

FLSA: Exempt

Department ID: 110701 - Animal Science

Department: 110701 - Animal Science

Job City & State: Raleigh, NC

Essential Job Duties: We invite applications for a 6-month postdoctoral research fellow to lead and contribute to method development and applied analyses in statistical genomic fine-mapping with a focus on dissecting the genetic architecture of inbreeding depression. The successful candidate will work closely with a multidisciplinary team to develop and apply statistical approaches to locate causal variants and genomic regions responsible for fitness declines associated with inbreeding, using large-scale genomic and phenotypic datasets.

Duties and Responsibilities

• Develop and apply statistical and computational methods for fine-mapping causal variants underlying inbreeding depression, including but not limited to Bayesian fine-mapping, mixed models, haplotype and ROH-based analyses, and rare-variant tests.
• Quantify and partition components of inbreeding depression across the genome.
• Integrate a range of data types where available (whole-genome sequence or high-density genotypes, pedigree records, phenotype/fitness measures, transcriptomics/functional annotation) to prioritize candidate loci and interpret biological mechanisms.
• Perform simulations to validate methods and assess power, false-discovery, and effect-size estimation under realistic demographic and genomic scenarios.
• Prepare manuscripts, present findings at group meetings and conferences, and contribute to grant or fellowship proposals.
• Collaborate with lab members and external collaborators; potentially supervise or mentor graduate/undergraduate students for parts of projects.

You Belong Here! At NC State, our goal is for all employees to reach their fullest potential at work. As you consider this opportunity, we encourage you to review our Employee Value Proposition and learn more about what makes NC State the best place to learn and work for everyone. Wolfpack Perks and Benefits: As a Pack member, you belong here, and can enjoy exclusive perks designed to enhance your personal and professional well-being. What we offer: Medical, Dental, Vision, Retirement and Leave; Faculty and Staff Assistance Program; Enhance your career with LEAD courses; Attend non-revenue generating sporting events for free. Attain Work-life balance with our Childcare benefits, Wellness & Recreation Membership, and Wellness Programs that aim to build a thriving wolfpack community. Work Schedule: Mon-Fri, 8am-5pm

Department Required Skills: PhD in statistical genetics, quantitative genetics, biostatistics, computational biology, population genetics, bioinformatics, or a closely related discipline.

Preferred Years Experience, Skills, Training, Education: Strong background in statistical modeling and quantitative methods (linear mixed models, Bayesian inference, likelihood methods). Proven experience working with large genomic datasets (GWAS, sequence, or high-density SNP arrays), and familiarity with runs of homozygosity (ROH), identity-by-descent (IBD), genotype imputation, and genomic relationship matrices. Experience with simulation frameworks. Good scientific communication skills and a record of peer-reviewed publications or strong.

Required License or Certification: n/a

Valid NC Driver's License required?: No

Commercial Driver's License Required?: No

Anticipated Hiring Range: $58,656

Job Open Date: 09/08/2025

Quick Link: https://jobs.ncsu.edu/postings/222699