groups consisting of PIs, postdoctoral scientists, PhD students and scientific officers. It is one of Europe's leading cancer research centres, supporting cutting-edge work into the molecular mechanisms of cancer development. As well as core support from Cancer Research UK, the Institute also receives an additional third of its total income from external grants and industry collaborations. It has an excellent reputation for fundamental cancer research, including world-class metabolism studies and renowned in vivo modelling of tumour growth and metastasis. Project outline We are seeking for a highly motivated postdoctoral fellow to join the laboratory of Prof. Danny Huang. The Huang Lab has a strong interest in understanding the structures, mechanisms and functions of ubiquitin ligases and how their deregulation contributes to cancer. The group has the expertise in recombinant protein expression and purification, structural characterization of protein complexes, and mechanistic analyses using both biochemical and cell-based approaches. Based at the CRUK Scotland Institute, we benefit from a collaborative environment and work closely with core facilities and other research groups to access advanced techniques, including proteomics, RNA sequencing analysis, advanced microscopy, and genetic mouse models. The candidate will have access to these technologies to support the development of the project. The ideal candidate will hold (or close to completing) a PhD in biochemistry or structural biology. Prior experience with Cryo-EM or research in the ubiquitin-related pathway is highly desirable. The successful applicant will take active role in structure determination using Cryo-EM and dissemination of results through publications and presentations. For informal enquiries, please email Prof. Danny Huang . Equality, Diversity and Inclusion Our vision is to build and maintain a diverse and inclusive research culture based on our shared values of Innovate, Respect, Integrity, Teamwork and Excellence. These values, which underpin our behaviours and everything we do, allow all our people to realise their full potential. The diversity of our staff and students is also what makes the Institute such a vibrant place to work and advance discoveries in cancer research. Family friendly policies, our collaborative ethos, a focus on good mental health and well-being and opportunities for all help to create an enjoyable and inclusive workplace where your voice matters. Employee Benefits Competitive salary 40.5 days annual leave including bank holidays (FTE) Defined contribution pension scheme Free life assurance scheme Employee Assistance Programme Interest free season ticket loans Additional maternity pay for 6 months at full salary Shared parental leave including up to 6 weeks paid at full salary Cycle to work scheme saving tax and NI on cycle purchase and spreading repayments over up to 12 months Access to employee benefit schemes with discounts on supermarkets, cinema, travel and much more. On-site secure parking All applications must be made via the ‘Apply’ button above.

groups consisting of PIs, postdoctoral scientists, PhD students and scientific officers. It is one of Europe's leading cancer research centres, supporting cutting-edge work into the molecular mechanisms of cancer development. As well as core support from Cancer Research UK, the Institute also receives an additional third of its total income from external grants and industry collaborations. It has an excellent reputation for fundamental cancer research, including world-class metabolism studies and renowned in vivo modelling of tumour growth and metastasis. Project outline We are seeking for a highly motivated postdoctoral fellow to join the laboratory of Prof. Danny Huang. The Huang Lab has a strong interest in understanding the structures, mechanisms and functions of ubiquitin ligases and how their deregulation contributes to cancer. The group has the expertise in recombinant protein expression and purification, structural characterization of protein complexes, and mechanistic analyses using both biochemical and cell-based approaches. Based at the CRUK Scotland Institute, we benefit from a collaborative environment and work closely with core facilities and other research groups to access advanced techniques, including proteomics, RNA sequencing analysis, advanced microscopy, and genetic mouse models. The candidate will have access to these technologies to support the development of the project. The ideal candidate will hold (or close to completing) a PhD in biochemistry or structural biology. Prior experience with Cryo-EM or research in the ubiquitin-related pathway is highly desirable. The successful applicant will take active role in structure determination using Cryo-EM and dissemination of results through publications and presentations. For informal enquiries, please email Prof. Danny Huang . Equality, Diversity and Inclusion Our vision is to build and maintain a diverse and inclusive research culture based on our shared values of Innovate, Respect, Integrity, Teamwork and Excellence. These values, which underpin our behaviours and everything we do, allow all our people to realise their full potential. The diversity of our staff and students is also what makes the Institute such a vibrant place to work and advance discoveries in cancer research. Family friendly policies, our collaborative ethos, a focus on good mental health and well-being and opportunities for all help to create an enjoyable and inclusive workplace where your voice matters. Employee Benefits Competitive salary 40.5 days annual leave including bank holidays (FTE) Defined contribution pension scheme Free life assurance scheme Employee Assistance Programme Interest free season ticket loans Additional maternity pay for 6 months at full salary Shared parental leave including up to 6 weeks paid at full salary Cycle to work scheme saving tax and NI on cycle purchase and spreading repayments over up to 12 months Access to employee benefit schemes with discounts on supermarkets, cinema, travel and much more. On-site secure parking All applications must be made via the ‘Apply’ button above.