26 Aug 2026

Job Information

Organisation/Company: CERBM
Research Field: Biological sciences
Researcher Profile: Recognised Researcher (R2)
Positions: Postdoc Positions
Application Deadline: 30 Nov 2026 - 00:00 (Europe/Paris)
Country: France
Type of Contract: Temporary
Job Status: Full-time
Is the job funded through the EU Research Framework Programme?: Other EU programme

Is the Job related to staff position within a Research Infrastructure?: No

Offer Description

We are looking for a highly motivated postdoctoral researcher to join the “Physiological and Pathological Mechanisms of Cortical Development” team led by Dr. Juliette Godin at the Institute of Genetics and Molecular and Cellular Biology (IGBMC) in Strasbourg, France. The Godin lab is a recognized expert in translational control during cortical development. The selected candidate will work under the direct supervision of Dr. Efil Bayam (CRCN Inserm), in the framework of the ANR-funded project SpeaDAT, which investigates the species-specific mechanisms of ADAT tRNA deaminase complex dysfunction in brain development. The postdoctoral researcher will study species-specific ADAT functions in progenitors and neurons and characterize impact of ADAT dysfunction on tRNAs and translational programs using human iPSC- and mouse ESCs -derived models, including 2D cortical neural stem cells/neurons and 3D cortical organoids carrying ADAT2 and ADAT3 pathogenic variants. This 30-month position is well suited to a recently graduated PhD experienced with human iPSC culture and/or 2D/3D neural differentiation protocols.

The candidate will generate and characterize human iPSC-derived 2D cortical neural stem cells, neurons and 3D cortical organoids carrying ADAT2 and ADAT3 pathogenic variants, assess cellular phenotypes (proliferation, cell cycle dynamics, progenitor identity, neuronal maturation and synaptic integration) using immunofluorescence, EdU/pulse-chase labeling and functional assays (MEA, calcium imaging) and analyze and interpret human mim-tRNA-seq and ribosome profiling data to characterize species-specific tRNA and translational programs in close collaboration with a bioinformatician.

Present research findings at team and consortium meetings and at national/international conferences, contribute to manuscript writing and to project reporting; contribute to the supervision of students.

Where to apply

E-mail: untereis@igbmc.fr

Requirements

Research Field: Biological sciences
Education Level: PhD or equivalent

Skills/Qualifications

Ph.D in Cell Biology, Molecular Biology, Developmental Biology, Neuroscience or a related field, recently obtained.
Experience with human iPSC culture and/or 2D/3D neural differentiation protocols is required.
Proficiency in standard molecular and cell biology techniques (immunofluorescence, western blot, qPCR, imaging)
Familiarity with high-throughput sequencing approaches (RNA-seq, ribosome profiling) is a plus
Interest in neurodevelopment, neurodevelopmental disorders and translational control
Fast learner, critical thinking, positive attitude, strong problem-solving skills and adaptability to new data and questions
Good interpersonal skills and ability to work within an interdisciplinary, international consortium
Strong written and oral communication skills in English
Strong organizational skills, personal motivation and creativity

Languages

ENGLISH
Level: Good

Work Location(s)

Number of offers available: 1
Company/Institute: INSERM
Country: France

Contact

City: Illkirch (Strasbourg)
Website: http://www.igbmc.fr/
Street: rue Laurent Fries 1
Postal Code: 67404

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Postdoctoral Researcher – Species-Specific ADAT Function in Cortical Development

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Illkirch (Strasbourg), France

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Postdoctoral Researcher – Species-Specific ADAT Function in Cortical Development

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This is a Preview Listing…

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Postdoctoral Researcher – Species-Specific ADAT Function in Cortical Development

Post My Job

Illkirch (Strasbourg), France

Job Information

This is a Preview Listing…

Related Jobs - August 28, 2026

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