Primary Work Address: 6001 Forest Park Road, Dallas, TX,
[contact details available in the full listing]
Current
HHMI Employees, click here to apply via your Workday
account.
The Howard Hughes Medical Institute (HHMI) advances the discovery
and sharing of scientific knowledge to benefit us all. As a
biomedical research organization and philanthropy, HHMI supports a
vibrant community of academic researchers, educators, students, and
professionals. Together, we're unlocking the fundamentals of
biology and building an open, inclusive future for science.
Lab Overview
The Orth Laboratory, led by HHMI Investigator Dr. Kim Orth at UT
Southwestern Medical Center in Dallas, Texas, investigates the
molecular mechanisms by which pathogenic bacteria manipulate host
cell signaling and immune responses. The lab's research integrates
microbiology, biochemistry, cell biology, structural biology, and
animal models to understand host-pathogen interactions at the
molecular level — with the goal of gaining novel molecular insight
into eukaryotic signaling systems. For more information, visit
https://labs.utsouthwestern.edu/orth-lab
About the Role
We are seeking a highly motivated
Postdoctoral Scientist to
join the Orth Lab at UT Southwestern Medical Center. This is an
exciting opportunity to investigate the molecular mechanisms by
which bacterial pathogens manipulate host cell signaling and immune
responses in a dynamic, interdisciplinary research environment. The
successful candidate will work primarily independently on their own
research project, developing their scientific program and
contributing to the lab's broader mission of understanding
host-pathogen interactions at the molecular level.
Application Instructions
Interested candidates should submit the following materials
directly through the HHMI Careers portal:
- Cover letter stating research interests and career goals
- Contact information for three professional references
What We Provide
- A competitive compensation package with comprehensive HHMI
health and wellness benefits.
- A highly collaborative and interdisciplinary research
environment at UT Southwestern Medical Center.
- Access to outstanding core facilities and scientific
resources.
- Opportunity to apply for external fellowships to support
independent research.
- Mentorship and career development opportunities in scientific
leadership.
What You'll Do
- Independently design and execute experiments investigating
molecular mechanisms of bacterial pathogenesis and host cell
signaling.
- Conduct research integrating microbiology, biochemistry, cell
biology, and structural biology approaches.
- Perform tissue culture, invasion studies, structural work, and
cellular pathway analyses.
- Analyze, interpret, and present experimental data in lab
meetings, seminars, and scientific conferences.
- Prepare and contribute to peer-reviewed manuscripts and
publications.
- Collaborate actively with other lab members, postdocs, and
members of the broader research community.
What You Bring
Required:
- A PhD in Microbiology, Molecular Biology, Biochemistry, Cell
Biology, Immunology, or a related field.
- A strong publication record — multiple first-author or co-first
author publications in reputable journals required.
- Hands-on experience in molecular biology, microbiology,
biochemistry, cell biology, or related techniques.
- Ability to independently design and execute experiments without
reliance on technicians.
- Excellent written and verbal communication skills and the
ability to work collaboratively.
Preferred:
- Experience in structural biology, host-pathogen interactions,
or cell signaling pathways.
- Familiarity with animal models used in infectious disease or
immunology research.
Physical Requirements
Remaining in a normal seated or standing position for extended
periods of time; reaching and grasping by extending hand(s) or
arm(s); dexterity to manipulate objects with fingers, for example
using a keyboard; communication skills using the spoken word;
ability to see and hear within normal parameters; ability to move
about workspace. The position requires mobility, including the
ability to move materials weighing up to several pounds (such as a
laptop computer or tablet).
Persons with disabilities may be able to perform the essential
duties of this position with reasonable accommodation. Requests for
reasonable accommodation will be evaluated on an individual
basis.
Please Note:
This job description sets forth the job’s principal duties,
responsibilities, and requirements; it should not be construed as
an exhaustive statement, however. Unless they begin with the word
“may,” the Essential Duties and Responsibilities described above
are “essential functions” of the job, as defined by the Americans
with Disabilities Act.
Compensation and Benefits
Our employees are compensated from a total rewards perspective in
many ways for their contributions to our mission, including
competitive pay, exceptional health benefits, retirement plans,
time off, and a range of recognition and wellness programs. Visit
our
Benefits at HHMI site to learn more.
Hiring Pay Range
$70,000.00 - $82,250.00
Pay Type:
Annual
The posted range reflects HHMI’s good faith estimate of the
anticipated hiring salary range for this role at the time of
posting. Actual hiring compensation is determined by a candidate’s
qualifications, experience, and internal equity.
HHMI is an Equal Opportunity
Employer
We use
E-Verify to confirm the identity and employment
eligibility of all new hires.