HHMI is focused on supporting and moving science forward in a variety of different ways ranging from conducting basic biomedical research, empowering educators, inspiring students, developing the next generation of scientists – even stretching into film and media production. Our Headquarters is in the greater Washington, DC metro area and is home to over 300 employees with expertise in investments, communications, digital production, biomedical sciences, and everything in between. The work housed here supports and augments the groundbreaking research conducted in HHMI labs across the nation.

The Opportunity

Howard Hughes Medical Institute (HHMI) is one of the largest private funders of biomedical research in the world, supporting hundreds of scientists at leading universities, hospitals, and research institutes, a dedicated research campus outside of Washington, DC that is the home of the AI@HHMI initiative, and national programs in science education, film and television, and AI-enabled research. The HHMI Presidential Fellows Program places a small cohort of exceptional early-career professionals (2–3 per year) directly in the Office of the President, working on the institute’s highest-priority strategic initiatives.

Fellows report to the President and the Vice President, Chief Operating Officer, and Senior Advisor to the President. This is not a rotation or an observation post. Fellows own projects, move them forward, and engage senior leadership for guidance and decision-making. The role is modeled on the federal Special Assistant to the President: high trust, high access, and high output.

What Fellows Do

• Lead cross-functional strategic projects spanning science programs, AI, finance, communications, human resources, technology, science education, and film
• Take initiatives from concept to the 20-yard line: scoping problems, building options, engaging the right people, and driving toward decisions
• Manage AI agents and LLM-based workflows to accelerate high-priority projects across the Institute
• Handle sensitive and confidential matters with discretion and sound judgment
• Dedicate 10% of their time to self-directed projects of their choosing, subject to approval by the President and COO

Who We’re Looking For

• Bachelor's degree required. We welcome both outstanding recent graduates and candidates with advanced degrees (MBA, MPP, PhD, JD, or equivalent) and 0 to 5 years of professional experience in consulting, policy, research, strategy, law, operations, or a comparable field
• Demonstrated ability to move between domains quickly, synthesizing information and driving action in unfamiliar territory
• Fluency with AI tools and large language models, including experience orchestrating AI agents to advance complex work
• Exceptional written and verbal communication skills, with a track record of producing clear, concise work product for senior audiences
• Comfort with ambiguity, shifting priorities, and the pace of executive-level decision-making
• Intellectual curiosity that spans the sciences, policy, technology, and institutional strategy