Regulation of neuronal excitability using IgG targeting of ion channels and GPCRs

About the Project

Academic Supervisor: Ewan Smith

Academic Institution: University of Cambridge

Industrial Partner: Maxion Therapeutics

Bioscience South Cambridge doctoral training Partnership (BioSCaPe) is a transformative PhD programme designed to create the bioscience leaders of tomorrow. Based in the heart of the world-leading Cambridgeshire bioscience cluster, BioSCaPe offers an unparalleled opportunity to combine cutting-edge research with entrepreneurial and leadership skills.

Starting January 2027, a 4-year Research Studentship will be available leading to a University of Cambridge PhD degree in the laboratory of Prof Ewan Smith.

Project Details

Our ability to detect internal and external stimuli depends upon specialised sensory neurons that are tuned to specific stimuli. ... (full project text on ion channels, GPCRs, KnotBody technology, collaboration with Prof. Graham Ladds, in vitro/in vivo characterisation, placement at Maxion Therapeutics).

Keywords: Ion channel, G protein-coupled receptor, electrophysiology, nociception, behaviour