Research Assistant (10390)

Rosalind Franklin Institute

We are seeking a highly motivated Research Assistant to support cutting-edge research in cell-cell interaction in epithelia. The role will focus on the development and genetic modification of human gut organoid and cell models, including the generation of fluorescently tagged proteins and disease-relevant phenotypes. The role will involve apply molecular biology techniques including DNA cloning, qPCR, and sequencing, CRISPR/Cas9 genome editing, advanced 2D and 3D cell culture, and fluorescence imaging techniques including super resolution. The post-holder will handle human tissue samples in compliance with HTA regulations and prepare growth factors for organoid maintenance.

The successful candidate will support a collaborative, multidisciplinary research environment.

Key Responsibilities

As a Research Assistant at the Franklin, you will become an integral part of the research team, supporting the work of scientists, by ensuring the smooth running of the labs. You will manage technologies and reagents and provide services to support the work of students and scientists of all levels. You may also be asked to undertake well defined experimental protocols in a supervised fashion.

You will also:

• Work with students and teams of researchers/technologists around established projects.
• Manage day to day running of the facilities and ensure that specific activities within the lab perform well.
• Keep meticulous records, ensuring compliance of lab processes, ordering and stocking, maintenance and operations.
• Support use of facilities, production of samples or performing aspects on behalf of researchers, with due consideration to health and safety.
• Be supervised by Lab Managers/Scientists.
• Be involved in scientific portfolio, including publications, projects or conferences.

Before submitting your application, please ensure you read the Job Information Pack for full details of this role on our website.

This job description set outs the skills and experience we believe are needed to be able to do this job but, research also tells us women are much more likely than men to take this list of requirements as absolute and self-select out of the process. If you think you can deliver this role then we want to hear from you, regardless of the boxes you did not tick.

To be considered for this role, please submit a CV and cover letter explaining why you think you are the right person for this job. Please include information about your education and work experience.

Closing date:The closing date for applications is 23:59 on Sunday 15th March 2026

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