University-Level Unit: Cancer Science Institute of Singapore
Faculty/Department-Level Unit: Research
Employee Category: Research Staff
Location_ONB: Kent Ridge Campus
Posting Start Date: 06/11/2026
Job Description
Principal Investigator: Prof Chng Wee Joo
The Research Assistant will support a comprehensive translational research programme which involves conducting laboratory-based experiments, managing human tumour samples, and supporting genomics- and proteomics-driven studies aimed at identifying clinically relevant biomarkers, disease subtypes, and therapeutic targets. The position contributes to the laboratory’s bench-to-bedside pipeline, supporting pre-clinical validation of discoveries prior to clinical translation.
Key Responsibilities
Laboratory Research & Experimental Work
- Perform molecular and cellular biology experiments (e.g., DNA/RNA extraction, qPCR, gene expression analysis, protein assasys and cell culture)
- Support high-throughput genomics and proteomics workflows (e.g., Microarray and next-generation sequencing (NGS) sample preparation)
- Assist in pre-clinical validation studies using cell lines and/or model systems.
Human Tumour Sample & Tissue Bank Support
- Handle and process human tumour samples in compliance with biosafety, ethical, and regulatory requirements.
- Assist in the maintenance of a comprehensive tissue bank, ensuring:
- Accurate sample labelling, storage, and inventory tracking
- Proper documentation for downstream genomic and proteomic analyses.
Data Management & Documentation
- Maintain accurate and detailed experimental records (laboratory notebooks and electronic systems).
- Assist with data entry and curation (e.g., clinical databases and relational databases used for integrated systems biology analysis)
- Support preparation of figures, tables, and summaries for presentations, reports, and publications.
General Laboratory Support
- Assist with laboratory organisation, reagent preparation, and equipment maintenance.
- Ensure compliance with institutional safety guidelines and SOPs.
- Participate in lab meetings, journal clubs, and training activities.
Requirements
Educational Qualifications
- Bachelor’s degree in Biomedical Science, Life Sciences, Molecular Biology, Genetics, Biochemistry, or a related discipline.
- Candidates with Honours or relevant research experience are preferred.
Technical Skills (Preferred)
- Basic experience in molecular biology techniques (DNA/RNA work, PCR, cell culture).
- Familiarity with genomics, sequencing platforms, or bioinformatics tools is an advantage.
- Experience handling human samples or working in a translational research setting is beneficial.
Soft Skills & Competencies
- Strong attention to detail and good organisational skills.
- Ability to work independently as well as collaboratively in a multidisciplinary research team.
- Good written and verbal communication skills.
- Willingness to learn new techniques and adapt to evolving research needs.
Req ID: 34929